Пластические реакции нейронов in vitro.
Структурно-функциональные взаимодействия молекулярных комплексов в процессе формирования адаптивных реакций
Пластические изменения ответов нейронов сопровождались локальными изменениями проницаемости участков мембраны для ионов. Было обнаружено, что разнонаправленные перестройки ответов сопровождались однотипными изменениями суммарных токов. Локальное увеличение входящих токов наблюдалось в нормальной и безнатриевой среде. Эти данные свидетельствуют об увеличении кальциевой проводимости при… Читать ещё >
Содержание
- Сокращения
- ВВЕДЕНИЕ
- ГЛАВА 1. ОБЗОР ЛИТЕРАТУРЫ
- 1.
- ГЛАВА. Субклеточные и молекулярные механизмы обучения
- Роль цитоскелета в организации физического 32 взаимодействия между участниками процессов восприятия внешних воздействий, проведения сигналов и формирования ответов клетки
- Роль структурообразующих белков в организации 47 взаимодействий ионных каналов и рецепторов плазматической мембраны с цитоскелетом и внутриклеточными протеинами
- Современная концепция структурной организации передачи 50 сигналов на клеточном уровне
- ГЛАВА 2. ОБЪЕКТ И МЕТОДЫ ИССЛЕДОВАНИЯ Объект исследования
- Методика получения и культивирования изолированных 68 нейронов
- Методы исследования электрической активности 71 изолированных нейронов
Алгоритмы применения воздействий, вызывавших 76 кратковременные пластические перестройки ответов. Алгоритмы применения воздействий, вызывавших 79 долговременные пластические реакции сомы изолированных нейронов
Приготовление растворов используемых веществ и способы 80 их аппликации.
Статистический анализ данных.
РЕЗУЛЬТАТЫ ОБСУЖДЕНИЕ ИССЛЕДОВАНИЯ
Кратковременные пластические реакции сомы 83 изолированных нейронов.
Пластические реакции нейронов, сформированные 83 локальными, одиночными электрическими воздействиями. Свойства пластических изменений ответов сомы 86 изолированных нейронов, вызванные локальными, одиночными электрическими воздействиями Пластические реакции, сформированные сочетанными 92 локальными и генерализованными электрическими воздействиями.
3.1.4 Свойства пластических изменений ответов сомы 93 изолированных нейронов вызванные сочетанными локальными и генерализованными электрическими воздействиями.
3.1.5 Реакции нейронов и функциональные изменения 98 электрогенных структур плазматической мембраны, вызванные локальной электрической стимуляцией по алгоритмам выработки привыкания и ассоциативного обучения.*
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