Реакции Уги и Пассерини в различных средах и в присутствии катализаторов
Диссертация
Принципиально иной подход заложен в синтезах, основанных на использовании муль-тикомпонентных реакций (МКР). Впервые термин «МКР» ввел в своих работах И. Уги. Мультикомпонентные реакции — реакции, протекающие при непосредственном смешении трех и более исходных соединений, причем конечная структура должна содержать фрагменты всех исходных. Все теоретически возможные МКР были разделены И. Уги… Читать ещё >
Содержание
- ГЛАВА 1. СПЕЦИФИЧНЫЙ КАТАЛИЗ МУЛЬТИКОМПОНЕНТНЫХ РЕАКЦИЙ
- 1. 1. Влияние растворителей на скорость и селективность МКР
- 1. 2. Влияние воды на скорость и селективность МКР
- 1. 3. МКР в мицеллярных растворах
- 1. 4. Кислоты Льюиса в качестве катализаторов МКР
- 1. 5. Высокое давление и МКР
- 1. 6. Микроволновое излучение для ускорения МКР
- 1. 7. Органические и неорганические материалы в качестве катализаторов МКР
- Выводы
- ГЛАВА 2. РЕАКЦИИ УГИ И ПАССЕРИНИ В РАЗЛИЧНЫХ СРЕДАХ И В ПРИСУТСТВИИ КАТАЛИЗАТОРОВ
- 2. 1. Синтез водорастворимых изоцианидов.'
- 2. 2. Изучение реакционной способности водорастворимых изоцианидов в реакции Уги
- 2. 3. Влияние воды и гетерогенных сред на протекание реакции Уги
- 2. 4. Реакция Пассерини в присутствии нуклеофильных добавок
- 2. 5. Синтез семичленных продуктов посредством реакции Уги
- 2. 5. 1. Новый метод синтеза производных 1,4-бензотиазепин-5-она
- 2. 5. 2. Синтез производных оптически активных кетокислот в водных растворах
- 2. 6. Новая мультикомпонентная реакция изоцианидов с использованием нуклеофильных добавок
- ГЛАВА 3. ЭКСПЕРИМЕНТАЛЬНАЯ ЧАСТ
- ВЫВОДЫ
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