Антропометрические, гормональные, рентгенологические и молекулярно-генетические проявления идиопатической низкорослости у детей
Диссертация
По данным популяционных исследований до 3% населения страдает низкорослостью. Изучение этиологии низкорослости является одним из приоритетных направлений в детской эндокринологии. В современной литературе широко обсуждаются вопросы клинических и гормонально-метаболических особенностей наиболее изученных причин задержки роста: соматотропной недостаточности, гипотиреоза, костных дисплазий… Читать ещё >
Содержание
- ГЛАВА 1. ОБЗОР ЛИТЕРАТУРЫ
- ГЛАВА 2. ХАРАКТЕРИСТИКА ОБСЛЕДОВАННОЙ ГРУППЫ ПАЦИЕНТОВ И МЕТОДЫ ИССЛЕДОВАНИЯ
- 2. 1. Характеристика обследованной группы пациентов
- 2. 2. Методы исследования
- ГЛАВА 3. РЕЗУЛЬТАТЫ СОБСТВЕННЫХ ИССЛЕДОВАНИЙ
- 3. 1. Исследование частоты встречаемости задержки роста у детей российской популяции
- 3. 2. Структура низкорослости пациентов, обследованных в ЭНЦ РАМН
- 3. 3. Сравнительная характеристика соматотропной недостаточности и идиопатической низкорослости
- 3. 4. Исследование зависимости параметров физического развития от уровня пика стимулированной секреции гормона роста у детей с идиопатической низкорослостью
- 3. 5. Сравнительная характеристика конституциональной задержки роста и семейной низкорослости
- 3. 6. Исследование липидов крови у детей с идиопатической низкорослостью
- 3. 7. Особенности MP-картины гипоталамо-гипофизарной области у пациентов с идиопатической низкорослостью
- 3. 8. Исследование гена SHOX у детей с идиопатической низкорослостью и синдромами, ассоциированными с SHOX, в российской популяции
- 3. 9. Терапия океандролоном мальчиков с идиопатической низкорослостью
- ГЛАВА 4. ОБСУЖДЕНИЕ СОБСТВЕННЫХ РЕЗУЛЬТАТОВ И
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