Влияние слабых комбинированных магнитных полей на регенерацию планарий Dugesia tigrina
Диссертация
Определена зависимость скорости регенерации планарий от соотношения амплитуд переменной и постоянной компонент комбинированного магнитного поля, а также от частоты переменной компонентыподтверждены соответствующие количественные предсказания теории. Провести экспериментальную проверку количественных предсказаний теории относительно зависимости эффектов комбинированного магнитного поля… Читать ещё >
Содержание
- Список сокращений
- 1. ОБЗОР ЛИТЕРАТУРЫ
- 1. Воздействие на биосистемы слабых магнитных полей
- 1. 1. Модель Либова («циклотронный» резонанс)
- 1. 2. Модель Леднева (параметрический резонанс)
- 1. 2. 1. Специфически связанные ионы как первичные мишени для воздействия МП
- 1. 2. 2. Количественные постулаты теории
- 1. 2. 3. Экспериментальная проверка основного постулата теории с использованием бесклеточных систем
- 1. 3. Влияние крайне слабых переменных магнитных полей
- КС ПеМП) на биосистемы
- 1. 3. 1. «Микротесловые» поля
- 1. 3. 2. «Нанотесловые» поля
- 1. 3. 3. «Пикотесловые» поля
- 2. Регенерирующие планарии как тест-система для изучения влияния магнитных полей на процессы пролиферации и роста
- 2. 1. Основные типы регенерации
- 2. 2. Планарии — классический объект в изучении регенерации и морфогенеза
- 2. 3. Необласты -тотипотентные резервные клетки
- 2. 4. Молекулярные аспекты регенерации
- Митогены, рецепторы, вторичные мессенджеры
- 2. 4. 1. Гормональная регуляция
- 2. 4. 2. Роль ионов кальция в индукции синтеза ДНК
- 2. 4. 3. Серотонин -ключевой регулятор на ранних стадиях регенерации
- 2. 4. 4. Протеинкиназа С
- 2. 4. 5. Рецепторы серотонина и G- белки
- 2. 5. Цели и задачи исследования
- 2. ОБЪЕКТЫ И МЕТОДЫ ИССЛЕДОВАНИЯ
- 2. 1. Модель регенерирующих планарий
- 2. 2. Определения пролиферативной активности необластов
- 2. 3. Метод прижизненной компьютерной морфометрии
- 2. 4. Техника получения магнитных полей
- 3. РЕЗУЛЬТАТЫ ИССЛЕДОВАНИЙ И ИХ ОБСУЖДЕНИЕ
- 3. 1. Активация пролиферации необластов при настройке переменной компоненты поля на параметрический резонанс для ионов кальция (Са -КМП) и магния (Mg2±KMn)
- 3. 2. Увеличение пролиферативной активности необластов при экспонировании в КМП, настроенном на параметрический резонанс ядерных спинов атомов водорода
- 3. 3. Ускорение и замедление формирования бластемы при экспонировании регенерирующих планарий в
- Са2±КМП и К± КМП, соответственно
- 3. 4. Совместное действие КМП и химических факторов на формирование бластемы
- 3. 5. Влияние крайне слабых переменных магнитных полей (КС ПеМП) с амплитудами в диапазоне 10"6−109 Тл на скорость регенерации
- ВЫВОДЫ
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