Клинические и метаболические аспекты гипогонадотропного гипогонадизма (ГГ) у больных с опухолями хиазмально-селлярной области (ХСО)
Диссертация
Актуальность работы обусловлена значительной распространенностью опухолей хиазмально-селлярной области (ХСО). Опухоли ХСО (или параселлярные опухоли) являются наиболее частой причиной гинопитуитаризма (173). По данным различных авторов частота встречаемости опухолей ХСО составляет 10−15% от всех внутричерепных образований (3, 17, 21). Они могут быть представлены различными морфологическими… Читать ещё >
Содержание
- СПИСОК СОКРАЩЕНИЙ
- ГЛАВА 1. ОБЗОР ЛИТЕРАТУРЫ
- 1. 1. Клинические проявления гипогонадотропного гипогонадизма при различных опухолях хиазмально-селлярной области
- 1. 2. Метаболические эффекты половых гормонов на органы и системы в норме и при опухолях ХСО
- 1. 2. 1. Влияние половых гормонов на костный метаболизм
- 1. 2. 3. Влияние половых гормонов на функциональное состояние центральной нервной системы
- 1. 2. 2. Влияние половых стероидов на сердечно-сосудистую систему
- 1. 3. Современная концепция о механизме действия половых гормонов
- ГЛАВА 2. МАТЕРИАЛЫ И МЕТОДЫ
- 2. 1. Клиническая характеристика больных
- 2. 2. Критерии исключения
- 2. 3. Методы исследования
- ГЛАВА 3. РЕЗУЛЬТАТЫ СОБСТВЕННЫХ ИССЛЕДОВАНИЙ
- 3. 1. Клиническая характеристика больных
- 3. 2. Клинические проявления опухолей хиазмально-селлярной области
- 3. 3. Клинические проявления гипогонадотропного гипогонадизма и гонадотропная функция гипофиза у больных с различными опухолями хиазмально-селлярной области
- 3. 4. Результаты исследования показателей костного метаболизма
- 3. 5. Результаты исследования показателей жирового обмена
- 3. 6. Результаты исследования психического статуса больных
- 3. 7. Результаты исследования концентрации ядерных рецепторов к эстрадиолу в клетках опухолей хиазмально-селлярной области
- ГЛАВА 4. ОБСУЖДЕНИЕ РЕЗУЛЬТАТОВ
- ВЫВОДЫ
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