Π₯Π°ΡΠ°ΠΊΡΠ΅ΡΠΈΡΡΠΈΠΊΠ° Π½ΠΎΠ²ΠΎΠ³ΠΎ ΡΠ΅ΠΌΠ΅ΠΉΡΡΠ²Π° ΡΠ°ΠΉΡ-ΡΠΏΠ΅ΡΠΈΡΠΈΡΠ΅ΡΠΊΠΈΡ ΡΠ½Π΄ΠΎΠ½ΡΠΊΠ»Π΅Π°Π·, ΠΊΠΎΠ΄ΠΈΡΡΠ΅ΠΌΡΡ Π’5-ΠΏΠΎΠ΄ΠΎΠ±Π½ΡΠΌΠΈ Π±Π°ΠΊΡΠ΅ΡΠΈΠΎΡΠ°Π³Π°ΠΌΠΈ
Π‘ΡΡΡΠΊΡΡΡΠ½Π°Ρ ΠΎΡΠ³Π°Π½ΠΈΠ·Π°ΡΠΈΡ, Π° ΡΠ°ΠΊΠΆΠ΅ ΡΠ·Π½Π°ΡΡΠΈΠ΅ ΡΠ²ΠΎΠΉΡΡΠ²Π° ΡΠ½Π΄ΠΎΠ½ΡΠΊΠ»Π΅Π°Π· ΡΠ΅ΠΌΠ΅ΠΉΡΡΠ² «GIY-YIG» ΠΈ «H-N-H» Π½Π°ΠΌΠ½ΠΎΠ³ΠΎ ΠΌΠ΅Π½Π΅Π΅ ΠΈΠ·ΡΡΠ΅Π½Ρ, ΡΠ΅ΠΌ Ρ ΠΏΡΠ΅Π΄ΡΡΠ°Π²ΠΈΡΠ΅Π»Π΅ΠΉ ΡΠ΅ΠΌΠ΅ΠΉΡΡΠ²Π° Ρ ΠΎΡΠΌΠΈΠ½Π³-ΡΠ½Π΄oΠ½yΠΊΠ»eaΠ·" LAGLIDADG". ΠΠ½Π΄ΠΎΠ½ΡΠΊΠ»Π΅Π°Π·ΡTevl (ΡΠ΅ΠΌΠ΅ΠΉΡΡΠ²ΠΎ «GIY-YIG») ΠΈ I-tfmwIΠ΅Π΄ΠΈΠ½ΡΡΠ²Π΅Π½Π½ΡΠ΅ ΠΏΡΠ΅Π΄ΡΡΠ°Π²ΠΈΡΠ΅Π»ΠΈ ΡΠΊΠ°Π·Π°Π½Π½ΡΡ ΡΠ΅ΠΌΠ΅ΠΉΡΡΠ² Ρ ΠΈΠ·Π²Π΅ΡΡΠ½ΠΎΠΉ ΡΡΡΡΠΊΡΡΡΠΎΠΉ ΠΊΠΎΠΌΠΏΠ»Π΅ΠΊΡΠΎΠ² Π±Π΅Π»ΠΎΠΊ-ΠΠΠ (Van Roey et al., 2001; Shen et al., 2004). Π ΡΠΎΡΡΠ°Π²Π΅ ΡΡΠΈΡ ΠΊΠΎΠΌΠΏΠ»Π΅ΠΊΡΠΎΠ² ΡΠΊΠ°Π·Π°Π½Π½ΡΠ΅… Π§ΠΈΡΠ°ΡΡ Π΅ΡΡ >
- Π‘ΠΎΠ΄Π΅ΡΠΆΠ°Π½ΠΈΠ΅
- ΠΡΠ΄Π΅ΡΠΆΠΊΠ°
- ΠΠΈΡΠ΅ΡΠ°ΡΡΡΠ°
- ΠΡΡΠ³ΠΈΠ΅ ΡΠ°Π±ΠΎΡΡ
- ΠΠΎΠΌΠΎΡΡ Π² Π½Π°ΠΏΠΈΡΠ°Π½ΠΈΠΈ
Π‘ΠΎΠ΄Π΅ΡΠΆΠ°Π½ΠΈΠ΅
- Π‘ΠΏΠΈΡΠΎΠΊ ΡΠΎΠΊΡΠ°ΡΠ΅Π½ΠΈΠΉ
- 1. ΠΠ±Π·ΠΎΡ Π»ΠΈΡΠ΅ΡΠ°ΡΡΡΡ
- 1. 1. Π₯ΠΎΡΠΌΠΈΠ½Π³-ΡΠ½Π΄ΠΎΠ½ΡΠΊΠ»Π΅Π°Π·Ρ
- 1. 2. H-N-H-ΡΠ½Π΄ΠΎΠ½ΡΠΊΠ»Π΅Π°Π·Ρ
- 1. 3. ΠΠ°ΡΠ°Π»ΠΈΡΠΈΡΠ΅ΡΠΊΠΈΠΉ ΡΠ΅Π½ΡΡ H-N-H-ΡΠ½Π΄ΠΎΠ½ΡΠΊΠ»Π΅Π°Π·
- 1. 3. 1. Π‘ΡΡΡΠΊΡΡΡΠ° ΠΊΠ°ΡΠ°Π»ΠΈΡΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΡΠ΅Π½ΡΡΠ° H-N-H-ΡΠ½Π΄ΠΎΠ½ΡΠΊΠ»Π΅Π°Π·
- 1. 3. 2. Π ΠΎΠ»Ρ ΠΈΠΎΠ½Π° ΠΌΠ΅ΡΠ°Π»Π»Π° Π² ΡΡΡΡΠΊΡΡΡΠ΅ Π°ΠΊΡΠΈΠ²Π½ΠΎΠ³ΠΎ ΡΠ΅Π½ΡΡΠ° H-N-H-ΡΠ½Π΄ΠΎΠ½ΡΠΊΠ»Π΅Π°Π·
- 1. 3. 3. ΠΠ΄ΠΈΠ½ΡΡΠ²ΠΎ ΡΡΡΡΠΊΡΡΡΠ½ΠΎΠΉ ΠΈ ΡΡΠ½ΠΊΡΠΈΠΎΠ½Π°Π»ΡΠ½ΠΎΠΉ ΠΎΡΠ³Π°Π½ΠΈΠ·Π°ΡΠΈΠΈ ΠΊΠ°ΡΠ°Π»ΠΈΡΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΡΠ΅Π½ΡΡΠ° Π½ΡΠΊΠ»Π΅Π°Π· ΡΡΠΏΠ΅ΡΡΠ΅ΠΌΠ΅ΠΉΡΡΠ²Π° «ΡΡΠ°-ΠΠ΅»
- 1. 3. 4. ΠΠΎΠ΄Π΅Π»Ρ ΠΊΠ°ΡΠ°Π»ΠΈΠ·Π° Π³ΠΈΠ΄ΡΠΎΠ»ΠΈΠ·Π° ΠΠΠ ΡΠ½Π΄ΠΎΠ½ΡΠΊΠ»Π΅Π°Π·Π°ΠΌΠΈ ΡΠ΅ΠΌΠ΅ΠΉΡΡΠ²Π° H-N-H
- 1. 4. ΠΠ΅Π½Π΅ΡΠΈΡΠ΅ΡΠΊΠ°Ρ ΡΠΎΠ»Ρ H-N-H-ΡΠ½Π΄ΠΎΠ½ΡΠΊΠ»Π΅Π°Π·
- 1. 5. Π£Π·Π½Π°Π²Π°Π½ΠΈΠ΅ ΠΠΠ-ΡΡΠ±ΡΡΡΠ°ΡΠΎΠ² Ρ
ΠΎΡΠΌΠΈΠ½Π³-ΡΠ½Π΄ΠΎΠ½ΡΠΊΠ»Π΅Π°Π·Π°ΠΌΠΈ
- 1. 5. 1. Π‘ΠΏΠ΅ΡΠΈΡΠΈΡΠ΅ΡΠΊΠΎΠ΅ ΡΠ·Π½Π°Π²Π°Π½ΠΈΠ΅ ΠΏΠΎΡΠ»Π΅Π΄ΠΎΠ²Π°ΡΠ΅Π»ΡΠ½ΠΎΡΡΠΈ
- 1. 5. 2. ΠΠ·Π°ΠΈΠΌΠΎΠ΄Π΅ΠΉΡΡΠ²ΠΈΠ΅ ΡΠ½Π΄ΠΎΠ½ΡΠΊΠ»Π΅Π°Π·Ρ l-Crel Ρ ΡΠ°ΠΉΡΠΎΠΌ ΡΠ·Π½Π°Π²Π°Π½ΠΈΡ
- 1. 5. 3. ΠΠ·Π°ΠΈΠΌΠΎΠ΄Π΅ΠΉΡΡΠ²ΠΈΠ΅ ΡΠ½Π΄ΠΎΠ½ΡΠΊΠ»Π΅Π°Π·Ρ 1-Π ΡΠΎ1 Ρ ΡΠ°ΠΉΡΠΎΠΌ ΡΠ·Π½Π°Π²Π°Π½ΠΈΡ
- 1. 5. 4. ΠΠ·Π°ΠΈΠΌΠΎΠ΄Π΅ΠΉΡΡΠ²ΠΈΠ΅ ΡΠ½Π΄ΠΎΠ½ΡΠΊΠ»Π΅Π°Π·Ρ I-7evI Ρ ΡΠ°ΠΉΡΠΎΠΌ ΡΠ·Π½Π°Π²Π°Π½ΠΈΡ
- 1. 5. 5. ΠΠ·Π°ΠΈΠΌΠΎΠ΄Π΅ΠΉΡΡΠ²ΠΈΠ΅ ΡΠ½Π΄ΠΎΠ½ΡΠΊΠ»Π΅Π°Π·Ρ l-Hmul Ρ ΡΠ°ΠΉΡΠΎΠΌ ΡΠ·Π½Π°Π²Π°Π½ΠΈΡ
- 2. 1. ΠΠ»Π°Π·ΠΌΠΈΠ΄Ρ
- 2. 2. Π¨ΡΠ°ΠΌΠΌΡ Π±Π°ΠΊΡΠ΅ΡΠΈΠΉ ΠΈ Π±Π°ΠΊΡΠ΅ΡΠΈΠΎΡΠ°Π³ΠΎΠ²
- 2. 3. ΠΠ°Π·ΠΎΠ²ΡΠ΅ ΠΌΠ΅ΡΠΎΠ΄Ρ ΠΌΠΎΠ»Π΅ΠΊΡΠ»ΡΡΠ½ΠΎΠΉ Π±ΠΈΠΎΠ»ΠΎΠ³ΠΈΠΈ ΠΈ Π±ΠΈΠΎΡ ΠΈΠΌΠΈΠΈ
- 2. 4. ΠΠΠ-ΡΡΠ±ΡΡΡΠ°ΡΡ
- 2. 5. ΠΠΎΠ»ΡΡΠ΅Π½ΠΈΠ΅ ΠΌΠ°ΡΡΠΈΡΠ½ΠΎΠΉ ΠΠΠ Π΄Π»Ρ ΡΡΠ°Π½ΡΠΊΡΠΈΠΏΡΠΈΠΈ in vitro
- 2. 6. Π’ΡΠ°Π½ΡΠΊΡΠΈΠΏΡΠΈΡ in vitro
- 2. 7. Π‘ΠΈΠ½ΡΠ΅Π· Π±Π΅Π»ΠΊΠ° Π² Π±Π΅ΡΠΊΠ»Π΅ΡΠΎΡΠ½ΠΎΠΉ ΡΠΈΡΡΠ΅ΠΌΠ΅ ΡΡΠ°Π½ΡΠ»ΡΡΠΈΠΈ ΠΈΠ· Π·Π°ΡΠΎΠ΄ΡΡΠ΅ΠΉ ΠΏΡΠ΅Π½ΠΈΡΡ
- 2. 8. ΠΠ½Π°Π»ΠΈΠ· Π½ΡΠΊΠ»Π΅Π°Π·Π½ΠΎΠΉ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ
- 2. 9. ΠΠ°ΡΡΠΈΡΠΎΠ²Π°Π½ΠΈΠ΅ ΡΠΎΡΠ΅ΠΊ ΡΠ°Π·ΡΡΠ²Π° ΠΠΠ
- 2. 10. ΠΠΊΡΠΏΡΠ΅ΡΡΠΈΡ ΠΈ ΠΎΡΠΈΡΡΠΊΠ° ΡΠ½Π΄ΠΎΠ½ΡΠΊΠ»Π΅Π°Π· F-777I ΠΈ F-777II
- 2. 11. ΠΠ°ΡΡΠΈΡΠΎΠ²Π°Π½ΠΈΠ΅ ΡΠ°ΠΉΡΠ° ΡΠ·Π½Π°Π²Π°Π½ΠΈΡ ΡΠ½Π΄ΠΎΠ½ΡΠΊΠ»Π΅Π°Π·Ρ F-Tflll
- 2. 11. 1. ΠΠ°ΡΠΈΡΠ° ΠΠΠ Π±Π΅Π»ΠΊΠΎΠΌ ΠΎΡ Π²ΠΎΠ·Π΄Π΅ΠΉΡΡΠ²ΠΈΡ ΠΠΠΠ°Π·Ρ I, Π³ΠΈΠ΄ΡΠΎΠΊΡΠΈΠ»ΡΠ½ΡΡ
ΡΠ°Π΄ΠΈΠΊΠ°Π»ΠΎΠ² ΠΈ Π΄ΠΈΠΌΠ΅ΡΠΈΠ»ΡΡΠ»ΡΡΠ°ΡΠ°
- 2. 11. 1. 1. ΠΠ°ΡΠΈΡΠ° ΠΎΡ ΠΠΠΠ°Π·Ρ
- 2. 11. 1. 2. ΠΠ°ΡΠΈΡΠ° ΠΎΡ Π³ΠΈΠ΄ΡΠΎΠΊΡΠΈΠ»ΡΠ½ΡΡ ΡΠ°Π΄ΠΈΠΊΠ°Π»ΠΎΠ²
- 2. 11. 1. 3. ΠΠ°ΡΠΈΡΠ° ΠΎΡ Π΄ΠΈΠΌΠ΅ΡΠΈΠ»ΡΡΠ»ΡΡΠ°ΡΠ°
- 2. 11. 1. ΠΠ°ΡΠΈΡΠ° ΠΠΠ Π±Π΅Π»ΠΊΠΎΠΌ ΠΎΡ Π²ΠΎΠ·Π΄Π΅ΠΉΡΡΠ²ΠΈΡ ΠΠΠΠ°Π·Ρ I, Π³ΠΈΠ΄ΡΠΎΠΊΡΠΈΠ»ΡΠ½ΡΡ
ΡΠ°Π΄ΠΈΠΊΠ°Π»ΠΎΠ² ΠΈ Π΄ΠΈΠΌΠ΅ΡΠΈΠ»ΡΡΠ»ΡΡΠ°ΡΠ°
- 2. 11. 3. Π‘Π΅ΠΊΠ²Π΅Π½ΠΈΡΠΎΠ²Π°Π½ΠΈΠ΅ ΠΠΠ-ΡΡΠ±ΡΡΡΠ°ΡΠ° ΠΏΠΎ ΠΠ°ΠΊΡΠ°ΠΌΡ-ΠΠΈΠ»Π±Π΅ΡΡΡ (A+G)
- 2. 11. 4. ΠΠ½Π°Π»ΠΈΠ· ΡΠ°ΡΡΠ΅ΠΏΠ»Π΅Π½Π½ΡΡ ΡΡΠ°Π³ΠΌΠ΅Π½ΡΠΎΠ² ΠΠΠ
- 2. 11. 5. ΠΠΎΠ»ΠΈΡΠ΅ΡΡΠ²Π΅Π½Π½Π°Ρ ΠΎΠ±ΡΠ°Π±ΠΎΡΠΊΠ° ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΠΎΠ²
- 2. 12. ΠΠΎΠΌΠΏΡΡΡΠ΅ΡΠ½ΡΠΉ Π°Π½Π°Π»ΠΈΠ· Π°ΠΌΠΈΠ½ΠΎΠΊΠΈΡΠ»ΠΎΡΠ½ΡΡ ΠΏΠΎΡΠ»Π΅Π΄ΠΎΠ²Π°ΡΠ΅Π»ΡΠ½ΠΎΡΡΠ΅ΠΉ
- 2. 13. ΠΠ»ΠΈΠ³ΠΎΠ½ΡΠΊΠ»Π΅ΠΎΡΠΈΠ΄Ρ
3. Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ 3.1. Π ΠΎΠ±Π»Π°ΡΡΠΈ Π³Π΅Π½ΠΎΠ² ΡΠ ΠΠ Π±Π°ΠΊΡΠ΅ΡΠΈΠΎΡΠ°Π³ΠΎΠ² Π’5 ΠΈ BF23 Escherichia coli, Π° ΡΠ°ΠΊΠΆΠ΅ Π±Π°ΠΊΡΠ΅ΡΠΈΠΎΡΠ°Π³Π° 5 Salmonella enterica sv. Heidelberg ΠΎΠ±Π½Π°ΡΡΠΆΠ΅Π½Ρ OPC, ΠΊΠΎΠ΄ΠΈΡΡΡΡΠΈΠ΅ ΠΏΡΠ΅Π΄ΠΏΠΎΠ»Π°Π³Π°Π΅ΠΌΡΠ΅ H-N-H-ΡΠ½Π΄ΠΎΠ½ΡΠΊΠ»Π΅Π°Π·Ρ.
3.2. ΠΠ΅Π½Ρ hegA, hegB, hegC ΠΈ hegD ΠΊΠΎΠ΄ΠΈΡΡΡΡ ΡΠ°ΠΉΡ-ΡΠΏΠ΅ΡΠΈΡΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΡΠ½Π΄ΠΎΠ½ΡΠΊΠ»Π΅Π°Π·Ρ.
3.3. ΠΡΡΠ²Π»Π΅Π½ΠΈΠ΅ Π΄ΠΎΠΏΠΎΠ»Π½ΠΈΡΠ΅Π»ΡΠ½ΡΡ ΡΠ°ΠΉΡΠΎΠ² Π³ΠΈΠ΄ΡΠΎΠ»ΠΈΠ·Π° ΡΠ½Π΄ΠΎΠ½ΡΠΊΠ»Π΅Π°Π· F-Π©, F-Tflll ΠΈ F-T/ΠΠ.
3.4. Π Π°Π·ΡΠ°Π±ΠΎΡΠ°Π½Π° ΡΡ Π΅ΠΌΠ° Π²ΡΠ΄Π΅Π»Π΅Π½ΠΈΡ ΠΈ ΠΎΡΠΈΡΡΠΊΠΈ ΡΠ½Π΄ΠΎΠ½ΡΠΊΠ»Π΅Π°Π· F-Tfll ΠΈ F-Tflll.
3.5. ΠΠ½Π΄ΠΎΠ½ΡΠΊΠ»Π΅Π°Π·Ρ F-Tfll ΠΈ F-Tflll Π½Π°ΠΈΠ±ΠΎΠ»Π΅Π΅ Π°ΠΊΡΠΈΠ²Π½Ρ ΠΏΡΠΈ ΡΠΊΡΡΡΠ΅ΠΌΠ°Π»ΡΠ½ΡΡ Π·Π½Π°ΡΠ΅Π½ΠΈΡΡ ΡΠ ΠΈ ΡΠ΅ΠΌΠΏΠ΅ΡΠ°ΡΡΡΡ.
3.6. ΠΠΊΡΠΈΠ²Π½ΠΎΡΡΡ ΡΠ½Π΄ΠΎΠ½ΡΠΊΠ»Π΅Π°Π· F-Tfll ΠΈ F-Tflll ΡΡΠΈΠΌΡΠ»ΠΈΡΡΠ΅ΡΡΡ ΡΠΈΡΠΎΠΊΠΈΠΌ ΡΡΠ΄ΠΎΠΌ ΠΈΠΎΠ½ΠΎΠ² Π΄Π²ΡΡ Π²Π°Π»Π΅Π½ΡΠ½ΡΡ ΠΌΠ΅ΡΠ°Π»Π»ΠΎΠ².
3.7. ΠΠΎΠ½ Zn, ΠΏΠΎ-Π²ΠΈΠ΄ΠΈΠΌΠΎΠΌΡ, ΡΡΠ°Π±ΠΈΠ»ΠΈΠ·ΠΈΡΡΠ΅Ρ ΡΡΡΡΠΊΡΡΡΡ ΠΈΠ·ΡΡΠ°Π΅ΠΌΡΡ Π½ΡΠΊΠ»Π΅Π°Π·.
3.8. ΠΠ½Π΄ΠΎΠ½ΡΠΊΠ»Π΅Π°Π·Π° F-Tflll ΡΠΏΠ΅ΡΠΈΡΠΈΡΠ½ΠΎ ΡΠ²ΡΠ·ΡΠ²Π°Π΅ΡΡΡ Ρ Π΄Π²ΡΠΌΡ ΡΡΠ°ΡΡΠΊΠ°ΠΌΠΈ ΠΠΠ, ΡΠ°ΡΠΏΠΎΠ»ΠΎΠΆΠ΅Π½Π½ΡΠΌΠΈ Π½Π° ΠΏΡΠΎΡΠΈΠ²ΠΎΠΏΠΎΠ»ΠΎΠΆΠ½ΡΡ ΠΊΠΎΠ½ΡΠ°Ρ ΡΠ°ΠΉΡΠ° ΡΠ·Π½Π°Π²Π°Π½ΠΈΡ.
3.8.1. ΠΠ½Π΄ΠΎΠ½ΡΠΊΠ»Π΅Π°Π·Π° F-Tflll ΡΠ²ΡΠ·ΡΠ²Π°Π΅Ρ ΠΏΡΠΎΡΡΠΆΠ΅Π½Π½ΡΠΉ ΡΡΠ°ΡΡΠΎΠΊ ΠΠΠ.
3.8.2. ΠΠΎΠ½ΡΠ°ΠΊΡΡ ΡΠ½Π΄ΠΎΠ½ΡΠΊΠ»Π΅Π°Π·Ρ F-Tflll Ρ ΠΎΡΡΠΎΠ²ΠΎΠΌ ΠΠΠ ΡΠ°ΡΠΏΡΠ΅Π΄Π΅Π»Π΅Π½Ρ ΠΏΠΎ Π²ΡΠ΅ΠΌΡ ΡΠ°ΠΉΡΡ ΡΠ·Π½Π°Π²Π°Π½ΠΈΡ.
3.8.3. ΠΠΎΠ½ΡΠ°ΠΊΡΡ ΡΠ½Π΄ΠΎΠ½ΡΠΊΠ»Π΅Π°Π·Ρ F-Tflll Ρ ΠΎΡΠ½ΠΎΠ²Π°Π½ΠΈΡΠΌΠΈ ΡΠ°ΡΠΏΠΎΠ»ΠΎΠΆΠ΅Π½Ρ Π² Π΄Π²ΡΡ ΡΡΠ°ΡΡΠΊΠ°Ρ ΡΠ°ΠΉΡΠ° ΡΠ·Π½Π°Π²Π°Π½ΠΈΡ.
3.8.4. ΠΠ½Π΄ΠΎΠ½ΡΠΊΠ»Π΅Π°Π·Π° F-Tflll ΠΊΠΎΠ½ΡΠ°ΠΊΡΠΈΡΡΠ΅Ρ Ρ ΠΎΡΠ½ΠΎΠ²Π°Π½ΠΈΡΠΌΠΈ ΡΠ°ΠΉΡΠ° ΡΠ·Π½Π°Π²Π°Π½ΠΈΡ Π² ΠΎΡΠ½ΠΎΠ²Π½ΠΎΠΌ ΡΠΎ ΡΡΠΎΡΠΎΠ½Ρ Π±ΠΎΠ»ΡΡΠΎΠ³ΠΎ ΠΆΠ΅Π»ΠΎΠ±ΠΊΠ° ΠΠΠ.
3.8.5. ΠΠΎΠ½ΡΠ°ΠΊΡΡ Ρ ΠΎΡΡΠ°ΡΠΊΠ°ΠΌΠΈ ΡΠΎΡΡΠ°ΡΠΎΠ² ΠΎΡΡΠΎΠ²Π° ΠΠΠ Π½Π΅ ΡΡΡΠ΅ΡΡΠ²Π΅Π½Π½Ρ Π΄Π»Ρ ΠΎΠ±ΡΠ°Π·ΠΎΠ²Π°Π½ΠΈΡ ΠΊΠΎΠΌΠΏΠ»Π΅ΠΊΡΠ° F-37 711-ΠΠΠ.
4. ΠΠ±ΡΡΠΆΠ΄Π΅Π½ΠΈΠ΅.
ΠΡΠ²ΠΎΠ΄Ρ.
Π‘ΠΏΠΈΡΠΎΠΊ Π»ΠΈΡΠ΅ΡΠ°ΡΡΡΡ
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