Влияние дефицита и избытка железа на активность антиоксидантных ферментов и образование ферритина у растений хрустальной травки
Диссертация
Нарушение физиологических процессов у растений в условиях действия абиотических стрессов в значительной степени связано с повышенной генерацией активных форм кислорода (АФК). Неблагоприятные последствия развития окислительного стресса в данной работе рассматриваются в связи с нарушением в клетках гомеостаза Fe. В этих условиях в клетках может накапливаться в свободной форме каталитически активное… Читать ещё >
Содержание
- ГЛАВА 1. ЛИТЕРАТУРНЫЙ ОБЗОР
- 1. 1. Роль железа в жизнедеятельности растений
- 1. 2. Содержание и формы Fe в почвах и механизмы поступления в растения
- 1. 3. Возможные последствия излишнего накопления Fe в растениях и механизмы поддержания его гомеостаза
- 1. 4. Ферритин: ультраструктурные особенности и функции в живых организмах
- 1. 4. 1. Ферритины прокариот
- 1. 4. 2. Ферритины животных
- 1. 4. 3. Ферритины растений
- 1. 4. 3. 1. Особенности строения ферритина у растений по данным молекулярных исследований
- 1. 4. 3. 2. Биосинтез ферритина у растений
- 1. 4. 3. 3. Компартментация ферритина в клетках и тканях растений и регуляция образования ферритина по данным электронной микроскопии
- 1. 4. 3. 4. Молекулярные механизмы регуляции биосинтеза ферритина
- 1. 4. 3. 5. Влияние избытка и дефицита железа на биосинтез ферритина
- 1. 4. 3. 6. Исследование биосинтеза и деградации ферритина в связи с развитием окислительного стресса
- 2. 1. Объект и условия выращивания растений в водной культуре
- 2. 2. Методы биохимических анализов
- 2. 2. 1. Определение содержания МДА
- 2. 2. 2. Определение содержания перекиси водорода
- 2. 2. 3. Определение активности СОД
- 2. 2. 4. Определение активности пероксидазы
- 2. 2. 5. Определение активности каталазы
- 2. 2. 6. Определение содержания пролина
- 2. 2. 7. Определение содержания белка в ферментных препаратах
- 2. 2. 8. Приготовление проб для определения содержания общего железа
- 2. 2. 9. Содержание хлорофилла (а + Ь)
- 2. 2. 10. Фиксация проб для электронно-микроскопических исследований
- 2. 2. 11. Проведение молекулярных анализов
- 2. 2. 11. 1. Выделение тотальной РНК фенол-хлороформным методом
- 2. 2. 11. 2. Очистка тотальной РНК от примесей ДНК
- 2. 2. 11. 3. Обратная транскрипция
- 2. 2. 11. 4. Подбор праймеров для проведения обратной полимеразной цепной реакции (ПЦР)
- 2. 2. 11. 5. Условия проведения ПЦР-анализа
- 2. 2. 11. 6. Подготовка проб для секвенирования нуклеотидных последовательностей генов ферритина
- 2. 2. 12. Проведение Вестерн-блоттинга для иммунодетекции ферритина
- 2. 2. 12. 1. Экстракция белков из тканей растения
- 2. 2. 12. 2. Проведение электрофореза в полиакриламидном геле
- 2. 2. 13. Математическая обработка данных
- 3. 1. Ответная реакция молодых растений на изменение содержания
- 3. 2. Ответная реакция взрослых растений на изменение содержания Fe3+ в среде выращивания в контрольных условиях и при засолении NaCl
- 3. 3. Дозовая зависимость изменения в листьях содержания железа и состояния окислительного стресса в пресных условиях и в присутствии NaCl
- 3. 4. Влияние дефицита и «избытка» Fe на состояние мембран, запасные включения и образование ферритина в пластидах в присутствии и в отсутствии в среде NaCl
- 4. 1. Идентификация генов ферритина, экспрессирующихся в листьях Mesembrianthemum crystallinum L
- 4. 2. Состояние экспрессии генов в листьях при дефиците железа и его избытке
- 4. 3. Влияние про-оксиданта параквата на экспрессию генов ферритина
- 4. 4. Влияние обработки листьев спермидином на экспрессию генов
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