Роль гормонов жировой ткани в развитии кардиоваскулярных заболеваний у женщин с субклиническим гипотиреозом
Диссертация
Есть целый ряд исследований, показавших связь субклинического гипотиреоза (СГ) с риском развития атеросклероза и инфаркта миокарда. В частности, результаты анализа Ротердамского исследования показали, что среди факторов риска развития заболеваний сердечно-сосудистой системы (ССС) СГ стоит на одной планке с другими более известными факторами риска. В тоже время, пока нет окончательной точки зрения… Читать ещё >
Содержание
- Глава 1. ОБЗОР ЛИТЕРАТУРЫ
- 1. 1. Субклинический гипотиреоз как фактор риска развития. сердечно-сосудистых осложнений
- 1. 1. 1. Основные подходы в лечении субклинического гипотиреоза
- 1. 2. Адипоцитокины
- 1. 2. 1. Лептин
- 1. 2. 1. 1. Лептин — структура, физиология, роль в развитии кардиоваскулярных поражений
- 1. 2. 1. 2. Лептин и гипоталамо-гипофизарно-тиреоидная ось
- 1. 2. 2. Резистин
- 1. 2. 2. 1. Резистин — структура, физиология, роль в развитии кардиоваскулярных поражений
- 1. 2. 2. 2. Резистин и гипоталамо-гипофизарно-тиреоидная система
- 1. 2. 3. Адипонектин
- 1. 2. 3. 1. Адипонектин — структура, физиология, роль в развитии кардиоваскулярных поражений
- 1. 2. 3. 2. Адипонектин и гипоталамо-гипофизарно-тиреоидная ось
- 1. 2. 4. Адипоцитокины и дисфункция щитовидной железы
- 1. 2. 4. 1. Адипонектин и нарушение функции щитовидной железы
- 1. 2. 4. 2. Лептин и нарушение функции щитовидной железы
- 1. 2. 4. 3. Резистин и нарушение функции щитовидной железы
- 1. 2. 1. Лептин
- 1. 1. Субклинический гипотиреоз как фактор риска развития. сердечно-сосудистых осложнений
- 2. 1. Материалы исследования
- 2. 2. Методы исследования
- 2. 3. Методы статистической обработки
- 3. 1. Результаты исследований женщин с субклиническим гипотиреозом без сердечно-сосудистых заболеваний
- 3. 1. 1. Сравнительный анализ антропометрических данных, лабораторных и инструментальных исследований
- 3. 1. 2. Сравнительная характеристика изучаемых параметров через 6 месяцев у пациенток СГ без ССЗ, получавших заместительную терапию левотироксином и находившихся без лечения
- 3. 2. Результаты исследований пациенток с субклиническим гипотиреозом и сердечно-сосудистыми заболеваниями
- 3. 2. 1. Сравнительная характеристика антропометрических данных, лабораторных и инструментальных исследований
- 3. 2. 2. Сравнительная характеристика изучаемых параметров через 6 месяцев у пациенток СГ с ССЗ, получавших заместительную терапию левотироксином и у пациенток, находившихся без лечения
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