Новые селективные пептидные субстраты цистеиновых пептидаз семейства папаина
Диссертация
Цистеиновые пептидазы семейства С1 (папаина) — обширная группа ферментов, схожих по первичной и пространственной структуре, а также по строению активного центра, каталитическому механизму, оптимальным условиям проявления каталитической активности. Для многих представителей семейства С1 проведен рентгеноструктурный анализ, на основании которого и данных по субстратной специфичности… Читать ещё >
Содержание
- СПИСОК СОКРАЩЕНИЙ
- 1. СПЕЦИФИЧНОСТЬ ЦИСТЕИНОВЫХ ПЕПТИДАЗ СЕМЕЙСТВА С1 (Обзор литературы)
- 1. 1. Классификация цистеиновых пептидаз
- 1. 2. Распространение, биологические функции и применение пептидаз семейства С
- 1. 3. Процессинг пептидаз семейства С
- 1. 4. Структура пептидаз семейства С
- 1. 5. Типы ферментативной активности пептидаз семейства С
- 1. 6. Активный центр и механизм катализа
- 1. 7. Активация и ингибирование ферментов
- 1. 8. Зона связывания пептидаз семейства С
- 1. 9. Группы, используемые для детекции ферментативного гидролиза пептидаз
- 1. 10. Субстраты пептидаз семейства С
- 1. 11. Специфичность пептидаз семейства С
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