Адъювантная химиотерапия в комплексном лечении злокачественных глиом супратенториальной локализации
Диссертация
По данным многих авторов частота выявления злокачественных опухолей головного мозга постоянно увеличивается (Modan В. et al., 1992; Legler J. M. et al., 1999; McKinley B. P. et al., 2000; Johannesen Т. B. et al., 2004; Sundeep Deorah, M. A. et al., 2006). По их мнению, заболеваемость злокачественными глиомами головного мозга в 1973 году составляла 6.1 случаев на 100 000 населения, тогда как… Читать ещё >
Содержание
- СПИСОК ИСПОЛЬЗУЕМЫХ СОКРАЩЕНИЙ
- ГЛАВА 1. Обзор литературы
- 1. 1. Определение, эпидемиология, классификация глиом
- 2. 2. Методы лечения глиом
- 2. 2. 1. Хирургическое лечение
- 2. 2. 2. Лучевая терапия
- 2. 2. 3. Химиотерапия
- 2. 2. 3. 1. Эффективность химиотерапии
- 2. 2. 3. 2. Химиорезистентность злокачественных глиом
- 2. 2. 3. 3. Индивидуализация адьювантной химиотерапии
- 2. 1. Принципы отбора пациентов
- 2. 2. Методы исследования
- 2. 3. Описание методик лечения
- 2. 3. 1. Хирургическое лечение
- 2. 3. 2. Лучевая терапия
- 2. 3. 3. Химиотерапия
- 2. 3. 3. 1. Химиотерапия с эмпирическим подбором цитостатического препарата
- 2. 3. 3. 2. Химиотерапия с индивидуальным подбором цитостатического препарата
- 3. 1. Различия клинических данных пациентов с анапластической астроцитомой и глиобластомой
- 4. 1. Хирургическое лечение
- 4. 2. Лучевая терапия
- 4. 3. Химиотерапия в комплексном лечении злокачественных глиом
- 4. 4. Осложнения химиотерапии
- 4. 5. Прогностические факторы
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