Π Π°Π·ΡΠ°Π±ΠΎΡΠΊΠ° ΡΠ΅ΡΡ-ΡΠΈΡΡΠ΅ΠΌΡ ΠΠ€Π Π΄Π»Ρ ΠΎΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΡ Π΄Π΅ΠΊΡΠ°ΠΌΠ΅ΡΠ°Π·ΠΎΠ½Π° Π² Π±ΠΈΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΡ ΡΡΠ±ΡΡΡΠ°ΡΠ°Ρ
ΠΠΈΡΡΠ΅ΡΡΠ°ΡΠΈΡ
Π‘ ΠΊΠ°Π»ΠΈΠ±ΡΠΎΠ²ΠΎΡΠ½Π°Ρ ΠΊΡΠΈΠ²Π°Ρ Π½Π΅ Π±ΡΠ»Π° Π»ΠΈΠ½Π΅ΠΉΠ½Π°. ΠΡΠΎ ΠΌΠΎΠΆΠ΅Ρ Π±ΡΡΡ ΡΠ²ΡΠ·Π°Π½ΠΎ Ρ ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΡΠΌΠΈ ΠΊΠΎΠ½ΡΠ΅Π½ΡΡΠ°ΡΠΈΠΉ Π·Π° ΡΡΠ΅Ρ ΠΈΡΠΏΠ°ΡΠ΅Π½ΠΈΡ ΡΠ΅Π°Π³Π΅Π½ΡΠΎΠ², ΠΎΡΠΎΠ±Π΅Π½Π½ΠΎ ΠΏΠΎ ΠΊΡΠ°ΡΠΌ ΠΏΠ»Π°Π½ΡΠ΅ΡΠ°, ΡΡΠΎ ΠΎΠ±ΡΡΠ½ΠΎ Π·Π½Π°ΡΠΈΡΠ΅Π»ΡΠ½ΠΎ ΡΠ½ΠΈΠΆΠ°Π΅Ρ ΡΠΎΡΠ½ΠΎΡΡΡ ΠΈΠ·ΠΌΠ΅ΡΠ΅Π½ΠΈΠΉ. ΠΠ»Ρ 2 ΡΠ°ΡΠΎΠ² ΠΏΡΠΈ 37 Β°C ΡΠ°ΠΊΠΆΠ΅ Π½Π°Π±Π»ΡΠ΄Π°Π΅ΡΡΡ Π½Π΅ΠΊΠΎΡΠΎΡΠ°Ρ Π½Π΅Π»ΠΈΠ½Π΅ΠΉΠ½ΠΎΡΡΡ, ΡΡΠΎ ΡΠ°ΠΊΠΆΠ΅ ΠΌΠΎΠΆΠ΅Ρ Π±ΡΡΡ ΡΠ²ΡΠ·Π°Π½ΠΎ Ρ «ΠΊΡΠ°Π΅Π²ΡΠΌΠΈ ΡΡΡΠ΅ΠΊΡΠ°ΠΌΠΈ». ΠΡΠ°ΡΠΈΠΊ Π·Π°Π²ΠΈΡΠΈΠΌΠΎΡΡΠΈ %Π‘ΠΠ’ ΠΎΡ ΠΊΠΎΠ½ΡΠ΅Π½ΡΡΠ°ΡΠΈΠΈ ΠΠ Π±ΡΠ» Π»ΠΈΠ½Π΅Π΅Π½ Π΄Π»Ρ ΡΡΠ»ΠΎΠ²ΠΈΠΉ ΠΈΠ½ΠΊΡΠ±Π°ΡΠΈΠΈ 1 ΡΠ°Ρ… Π§ΠΈΡΠ°ΡΡ Π΅ΡΡ >
- Π‘ΠΎΠ΄Π΅ΡΠΆΠ°Π½ΠΈΠ΅
- ΠΡΠ΄Π΅ΡΠΆΠΊΠ°
- ΠΠΈΡΠ΅ΡΠ°ΡΡΡΠ°
- ΠΡΡΠ³ΠΈΠ΅ ΡΠ°Π±ΠΎΡΡ
- ΠΠΎΠΌΠΎΡΡ Π² Π½Π°ΠΏΠΈΡΠ°Π½ΠΈΠΈ
Π‘ΠΎΠ΄Π΅ΡΠΆΠ°Π½ΠΈΠ΅
- 1. ΠΠΠΠΠΠΠΠ
- 2. ΠΠΠΠΠ ΠΠΠ’ΠΠ ΠΠ’Π£Π Π«
- 2. 1. Π‘ΡΠΈΠΌΡΠ»ΡΡΠΎΡΡ ΡΠΎΡΡΠ°
- 2. 2. ΠΠΎΡΡΠΈΠΊΠΎΡΡΠ΅ΡΠΎΠΈΠ΄Ρ
- 2. 3. ΠΠ΅ΠΊΡΠ°ΠΌΠ΅ΡΠ°Π·ΠΎΠ½
- 2. 4. Π€Π°ΡΠΌΠ°ΠΊΠΎΠΊΠΈΠ½Π΅ΡΠΈΠΊΠ° Π΄Π΅ΠΊΡΠ°ΠΌΠ΅ΡΠ°Π·ΠΎΠ½Π°
- 2. 5. Π€Π°ΡΠΌΠ°ΠΊΠΎΠ΄ΠΈΠ½Π°ΠΌΠΈΠΊΠ° Π΄Π΅ΠΊΡΠ°ΠΌΠ΅ΡΠ°Π·ΠΎΠ½Π°
- 2. 6. ΠΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΠ΅ ΠΏΡΠΈΠ΅ΠΌΠ»Π΅ΠΌΠΎΠΉ ΡΡΡΠΎΡΠ½ΠΎΠΉ Π΄ΠΎΠ·Ρ ΠΏΠΎΡΡΠ΅Π±Π»Π΅Π½ΠΈΡ ΠΠ
- 2. 7. Π Π°ΡΡΠ΅Ρ ΠΌΠ°ΠΊΡΠΈΠΌΠ°Π»ΡΠ½ΠΎ Π΄ΠΎΠΏΡΡΡΠΈΠΌΠΎΠ³ΠΎ ΡΡΠΎΠ²Π½Ρ ΠΎΡΡΠ°ΡΠΊΠΎΠ² ΠΠ
- 2. 8. ΠΠ΅ΡΠΈΠΎΠ΄ ΠΎΠΆΠΈΠ΄Π°Π½ΠΈΡ ΠΏΠΎΡΠ»Π΅ ΠΏΡΠΈΠΌΠ΅Π½Π΅Π½ΠΈΡ ΠΠ
- 2. 9. Π‘ΠΊΡΠΈΠ½ΠΈΠ½Π³-ΠΌΠ΅ΡΠΎΠ΄Ρ
- 2. 10. ΠΠΌΠΌΡΠ½ΠΎΡΠ΅ΡΠΌΠ΅Π½ΡΠ½ΡΠΉ Π°Π½Π°Π»ΠΈΠ· (ΠΠ€Π)
- 2. 11. ΠΠ΅ΡΠ΅ΡΠΎΠ³Π΅Π½Π½ΡΠΉ ΠΠ€Π
- 2. 12. ΠΡΠΈΠ½ΡΠΈΠΏΡ ΠΈΠΌΠΌΠΎΠ±ΠΈΠ»ΠΈΠ·Π°ΡΠΈΠΈ Π±ΠΈΠΎΠΌΠΎΠ»Π΅ΠΊΡΠ»
- 2. 13. Π€Π΅ΡΠΌΠ΅Π½ΡΠ°ΡΠΈΠ²Π½ΡΠ΅ ΠΌΠ΅ΡΠΊΠΈ Π² ΠΠ€Π
- 2. 14. ΠΡΠ±ΠΎΡ ΠΏΠΎΠ΄Ρ ΠΎΠ΄ΡΡΠ΅Π³ΠΎ ΡΡΠ±ΡΡΡΠ°ΡΠ° Π² ΠΠ€Π
- 2. 16. ΠΡΠ±ΠΈΡΡΠ°ΠΆΠ½ΡΠ΅ ΠΌΠ΅ΡΠΎΠ΄Ρ
- 2. 17. ΠΡΠ΅Π΄Π΅Π» ΠΎΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΡ ΠΌΠ΅ΡΠΎΠ΄Π°
- 2. 18. ΠΠΎΠ»ΡΡΠ΅Π½ΠΈΠ΅ ΠΈΠΌΠΌΡΠ½ΠΎΠ³Π΅Π½ΠΎΠ² ΠΈ ΠΈΠΌΠΌΡΠ½ΠΎΡΠ΅Π°Π³Π΅Π½ΡΠΎΠ²
- 2. 19. ΠΠΌΠΌΡΠ½Π½Π°Ρ ΡΠΈΡΡΠ΅ΠΌΠ° ΠΌΠ»Π΅ΠΊΠΎΠΏΠΈΡΠ°ΡΡΠΈΡ
- 2. 20. Π‘ΠΈΠ½ΡΠ΅Π· ΠΠ
- 2. 21. ΠΠΎΠ»ΠΈΡΠ΅ΡΡΠ²ΠΎ ΠΠ Π΄Π»Ρ ΠΈΠΌΠΌΡΠ½ΠΈΠ·Π°ΡΠΈΠΉ
- 2. 22. ΠΡΠ½ΠΎΠ²Π½ΡΠ΅ ΡΠ²ΠΎΠΉΡΡΠ²Π° Π°Π΄ΡΡΠ²Π°Π½ΡΠΎΠ²
- 2. 23. ΠΡΠ±ΠΎΡ Π°Π΄ΡΡΠ²Π°Π½ΡΠ°
- 2. 24. ΠΡΠ±ΠΎΡ ΠΆΠΈΠ²ΠΎΡΠ½ΠΎΠ³ΠΎ Π΄Π»Ρ ΠΏΡΠΎΠ΄ΡΠΊΡΠΈΠΈ ΠΏΠΎΠ»ΠΈΠΊΠ»ΠΎΠ½Π°Π»ΡΠ½ΡΡ AT
- 2. 25. ΠΡΡΠΈ Π²Π²Π΅Π΄Π΅Π½ΠΈΡ ΠΈ ΠΊΠΎΠ»ΠΈΡΠ΅ΡΡΠ²ΠΎ ΠΈΠ½ΡΠ΅ΠΊΡΠΈΠΉ Π΄Π»Ρ ΠΏΠ΅ΡΠ²ΠΈΡΠ½ΠΎΠΉ ΠΈΠΌΠΌΡΠ½ΠΈΠ·Π°ΡΠΈΠΈ
- 2. 26. ΠΠΎΠ²ΡΠΎΡΠ½ΡΠ΅ ΠΏΠΎΠ΄Π΄Π΅ΡΠΆΠΈΠ²Π°ΡΡΠΈΠ΅ ΠΈΠΌΠΌΡΠ½ΠΈΠ·Π°ΡΠΈΠΈ
- 2. 27. ΠΡΠΎΠ³ΡΠ°ΠΌΠΌΡ ΠΈΠΌΠΌΡΠ½ΠΈΠ·Π°ΡΠΈΠΉ
- 2. 28. ΠΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΠ΅ ΡΠ»Π΅Π΄ΠΎΠ² ΠΎΡΠ³Π°Π½ΠΈΡΠ΅ΡΠΊΠΈΡ ΡΠΎΠ΅Π΄ΠΈΠ½Π΅Π½ΠΈΠΉ
- 2. 29. ΠΠΈΠ΄ΠΊΠΎΡΡΠ½ΠΎ-ΠΆΠΈΠ΄ΠΊΠΎΡΡΠ½Π°Ρ ΡΠΊΡΡΡΠ°ΠΊΡΠΈΡ
- 2. 30. Π’Π΅Ρ Π½ΠΎΠ»ΠΎΠ³ΠΈΡ ΡΠΊΡΡΡΠ°ΠΊΡΠΈΠΈ
- 2. 31. ΠΠ΅ΡΠΎΠ΄Ρ ΡΠΊΡΡΡΠ°ΠΊΡΠΈΠΈ Π΄Π΅ΠΊΡΠ°ΠΌΠ΅ΡΠ°Π·ΠΎΠ½Π°
- 3. ΠΠΠ’ΠΠ ΠΠΠΠ« Π ΠΠΠ’ΠΠΠ« ΠΠ‘Π‘ΠΠΠΠΠΠΠΠΠ
- 3. 1. ΠΡΠΏΠΎΠ»ΡΠ·ΡΠ΅ΠΌΡΠ΅ ΡΠ΅Π°ΠΊΡΠΈΠ²Ρ ΠΈ ΠΌΠ°ΡΠ΅ΡΠΈΠ°Π»Ρ
- 3. 2. ΠΠ΅ΡΠΎΠ΄Ρ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠΉ
- 3. 2. 1. ΠΠΎΠ»ΡΡΠ΅Π½ΠΈΠ΅ Π³Π°ΠΏΡΠ΅Π½Π° ΠΈ ΠΊΠΎΠ½ΡΡΠ³Π°ΡΠΎΠ² Π΄Π΅ΠΊΡΠ°ΠΌΠ΅ΡΠ°Π·ΠΎΠ½Π° Ρ Π±Π΅Π»ΠΊΠ°ΠΌΠΈ
- 3. 2. 2. ΠΠΎΠ»ΡΡΠ΅Π½ΠΈΠ΅ ΡΠΏΠ΅ΡΠΈΡΠΈΡΠ΅ΡΠΊΠΈΡ ΠΏΠΎΠ»ΠΈΠΊΠ»ΠΎΠ½Π°Π»ΡΠ½ΡΡ ΡΡΠ²ΠΎΡΠΎΡΠΎΠΊ
- 3. 2. 3. Π‘Π΅Π½ΡΠΈΠ±ΠΈΠ»ΠΈΠ·Π°ΡΠΈΡ Π»ΡΠ½ΠΎΠΊ ΠΏΠ»Π°Π½ΡΠ΅ΡΠ°
- 3. 2. 4. ΠΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΠ΅ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ ΠΈΠΌΠΌΡΠ½Π½ΡΡ ΡΡΠ²ΠΎΡΠΎΡΠΎΠΊ
- 3. 2. 5. ΠΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΠ΅ ΡΠΏΠ΅ΡΠΈΡΠΈΡΠ½ΠΎΡΡΠΈ ΠΈ ΠΊΠΎΠ½ΡΡΠ°Π½ΡΡ Π°ΡΡΠΈΠ½Π½ΠΎΡΡΠΈ ΠΈΠΌΠΌΡΠ½Π½ΡΡ ΡΡΠ²ΠΎΡΠΎΡΠΎΠΊ
- 3. 2. 6. ΠΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΠ΅ ΡΠΏΠ΅ΡΠΈΡΠΈΡΠ½ΠΎΡΡΠΈ ΡΠ΅ΡΡ-ΡΠΈΡΡΠ΅ΠΌΡ
- 3. 2. 7. ΠΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΠ΅ ΠΊΠΎΠ½ΡΠ΅Π½ΡΡΠ°ΡΠΈΠΈ Π±Π΅Π»ΠΊΠ° ΠΏΠΎ ΠΌΠ΅ΡΠΎΠ΄Ρ ΠΠΎΡΡΠΈ
- 3. 2. 8. ΠΠΊΡΡΡΠ°ΠΊΡΠΈΡ ΠΠ ΠΈΠ· Π±ΠΈΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΡ
ΡΡΠ±ΡΡΡΠ°ΡΠΎΠ²
- 3. 2. 8. 1. ΠΠΎΠ΄Π³ΠΎΡΠΎΠ²ΠΊΠ° ΠΎΠ±ΡΠ°Π·ΡΠΎΠ² ΠΌΡΡΠ΅ΡΠ½ΠΎΠΉ ΡΠΊΠ°Π½ΠΈ ΠΠ Π‘
- 3. 2. 8. 2. ΠΠΎΠ΄Π³ΠΎΡΠΎΠ²ΠΊΠ° ΠΎΠ±ΡΠ°Π·ΡΠΎΠ² ΠΌΡΡΠ΅ΡΠ½ΠΎΠΉ ΡΠΊΠ°Π½ΠΈ ΡΠ²ΠΈΠ½ΡΠΈ
- 3. 2. 8. 3. ΠΠΎΠ΄Π³ΠΎΡΠΎΠ²ΠΊΠ° ΠΎΠ±ΡΠ°Π·ΡΠΎΠ² ΠΏΠ΅ΡΠ΅Π½ΠΈ
- 3. 2. 8. 4. ΠΠΎΠ΄Π³ΠΎΡΠΎΠ²ΠΊΠ° ΠΎΠ±ΡΠ°Π·ΡΠΎΠ² ΠΏΠΎΡΠ΅ΠΊ
- 3. 2. 8. 5. ΠΠΎΠ΄Π³ΠΎΡΠΎΠ²ΠΊΠ° ΠΎΠ±ΡΠ°Π·ΡΠΎΠ² ΠΌΠΎΡΠΈ
- 3. 2. 8. 6. ΠΠΎΠ΄Π³ΠΎΡΠΎΠ²ΠΊΠ° ΠΎΠ±ΡΠ°Π·ΡΠΎΠ² ΠΊΠΎΡΠΌΠ°
- 3. 2. 8. 7. ΠΠΎΠ΄Π³ΠΎΡΠΎΠ²ΠΊΠ° ΠΎΠ±ΡΠ°Π·ΡΠΎΠ² ΠΌΠΎΠ»ΠΎΠΊΠ°
- 3. 2. 9. ΠΡΠΎΠ²Π΅Π΄Π΅Π½ΠΈΠ΅ ΠΠΠΠ₯-ΠΠ‘-ΠΠ‘ Π°Π½Π°Π»ΠΈΠ·Π°
- 3. 2. 10. ΠΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΠ΅ ΠΊΠΎΠ½ΡΠ΅Π½ΡΡΠ°ΡΠΈΠΈ ΠΠ Π² ΠΈΡΡΠ»Π΅Π΄ΡΠ΅ΠΌΡΡ ΠΎΠ±ΡΠ°Π·ΡΠ°Ρ
- 3. 2. 11. ΠΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΠ΅ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ ΡΠΊΡΡΡΠ°ΠΊΡΠΈΠΈ ΠΠ ΠΈΠ· Π±ΠΈΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΡ ΡΡΠ±ΡΡΡΠ°ΡΠΎΠ²
- 3. 2. 12. Π Π°ΡΡΠ΅Ρ ΠΌΠ΅ΡΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΡ
Ρ
Π°ΡΠ°ΠΊΡΠ΅ΡΠΈΡΡΠΈΠΊ ΠΠ’Π ΠΠ€Π
- 3. 2. 12. 1. Π Π°ΡΡΠ΅Ρ ΠΏΡΠ΅Π΄Π΅Π»ΠΎΠ² ΠΎΠ±Π½Π°ΡΡΠΆΠ΅Π½ΠΈΡ ΠΈ ΠΎΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΡ ΠΠ Π² ΠΎΠ±ΡΠ°Π·ΡΠ°Ρ
- 3. 2. 12. 2. ΠΠΎΡΠΏΡΠΎΠΈΠ·Π²ΠΎΠ΄ΠΈΠΌΠΎΡΡΡ ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΠΎΠ² Π°Π½Π°Π»ΠΈΠ·Π°
- 3. 2. 12. 3. Π‘Ρ ΠΎΠ΄ΠΈΠΌΠΎΡΡΡ ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΠΎΠ² Π°Π½Π°Π»ΠΈΠ·Π°
- 3. 2. 13. ΠΠ±ΡΠ°Π±ΠΎΡΠΊΠ° Π΄Π°Π½Π½ΡΡ
- 4. 1. ΠΠΎΠ»ΡΡΠ΅Π½ΠΈΠ΅ ΡΠΏΠ΅ΡΠΈΡΠΈΡΠ΅ΡΠΊΠΈΡ ΠΈΠΌΠΌΡΠ½ΠΎΡΠ΅Π°Π³Π΅Π½ΡΠΎΠ²
- 4. 2. ΠΡΡΠ°Π±ΠΎΡΠΊΠ° ΡΡΠ»ΠΎΠ²ΠΈΠΉ ΠΏΡΠΎΠ²Π΅Π΄Π΅Π½ΠΈΡ ΠΏΡΠΎΡΠ΅Π΄ΡΡΡ ΠΠ’Π ΠΠ€Π
- 4. 2. 1. ΠΠΎΠ»ΡΡΠ΅Π½ΠΈΠ΅ ΡΠΏΠ΅ΡΠΈΡΠΈΡΠ΅ΡΠΊΠΈΡ ΠΈΠΌΠΌΡΠ½Π½ΡΡ ΡΡΠ²ΠΎΡΠΎΡΠΎΠΊ
- 4. 2. 2. ΠΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΠ΅ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ ΠΈΠΌΠΌΡΠ½Π½ΡΡ ΡΡΠ²ΠΎΡΠΎΡΠΎΠΊ Π² ΠΠ’ ΠΠ€Π
- 4. 2. 3. ΠΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΠ΅ ΡΠΏΠ΅ΡΠΈΡΠΈΡΠ½ΠΎΡΡΠΈ ΠΈΠΌΠΌΡΠ½Π½ΡΡ ΡΡΠ²ΠΎΡΠΎΡΠΎΠΊ Π² ΠΠ’Π ΠΠ€Π
- 4. 2. 4. ΠΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΠ΅ ΠΊΠΎΠ½ΡΡΠ°Π½Ρ Π°ΡΡΠΈΠ½Π½ΠΎΡΡΠΈ AT Π² ΠΠ’Π ΠΠ€Π
- 4. 2. 5. ΠΡΠ±ΠΎΡ Π’Π€Π Π΄Π»Ρ ΡΠ΅Π½ΡΠΈΠ±ΠΈΠ»ΠΈΠ·Π°ΡΠΈΠΈ ΠΈΠΌΠΌΡΠ½ΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΠΏΠ»Π°Π½ΡΠ΅ΡΠ°
- 4. 2. 6. ΠΡΠ±ΠΎΡ ΠΎΠΏΡΠΈΠΌΠ°Π»ΡΠ½ΠΎΠΉ ΠΊΠΎΠ½ΡΠ΅Π½ΡΡΠ°ΡΠΈΠΈ Π’Π€Π
- 4. 2. 7. ΠΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΠ΅ ΠΎΠΏΡΠΈΠΌΠ°Π»ΡΠ½ΠΎΠ³ΠΎ Π²ΡΠ΅ΠΌΠ΅Π½ΠΈ ΡΠ΅Π½ΡΠΈΠ±ΠΈΠ»ΠΈΠ·Π°ΡΠΈΠΈ ΠΈ ΠΎΠΏΡΠΈΠΌΠ°Π»ΡΠ½ΠΎΠΉ ΡΠ΅ΠΌΠΏΠ΅ΡΠ°ΡΡΡΡ ΠΈΠ½ΠΊΡΠ±Π°ΡΠΈΠΈ Π’Π€Π Ρ ΠΏΠΎΠ»ΠΈΡΡΠΈΡΠΎΠ»ΠΎΠΌ
- 4. 2. 8. ΠΡΠΎΠ²Π΅ΡΠΊΠ° ΡΠ°Π·Π»ΠΈΡΠ½ΡΡ ΠΈΠΌΠΌΡΠ½ΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΡ ΠΏΠ»Π°Π½ΡΠ΅ΡΠΎΠ² Π² ΠΠ’Π ΠΠ€Π
- 4. 2. 9. ΠΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΠ΅ ΠΎΠΏΡΠΈΠΌΠ°Π»ΡΠ½ΠΎΠ³ΠΎ Π²ΡΠ΅ΠΌΠ΅Π½ΠΈ ΠΈ ΡΠ΅ΠΌΠΏΠ΅ΡΠ°ΡΡΡΡ ΠΈΠ½ΠΊΡΠ±Π°ΡΠΈΠΈ Π’Π€Π Ρ AT Π² ΠΠ’Π ΠΠ€Π
- 4. 2. 10. ΠΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΠ΅ ΡΡΠ²ΡΡΠ²ΠΈΡΠ΅Π»ΡΠ½ΠΎΡΡΠΈ ΠΏΡΠ΅Π΄Π»Π°Π³Π°Π΅ΠΌΠΎΠ³ΠΎ ΠΌΠ΅ΡΠΎΠ΄Π° Π΄Π»Ρ ΠΎΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΡ ΠΠ
- 4. 2. 11. ΠΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΠ΅ ΡΠΏΠ΅ΡΠΈΡΠΈΡΠ½ΠΎΡΡΠΈ ΡΠ΅ΡΡ-ΡΠΈΡΠ΅ΠΌΡ
Π‘ΠΏΠΈΡΠΎΠΊ Π»ΠΈΡΠ΅ΡΠ°ΡΡΡΡ
- ΠΠ°ΠΉΠ΅ΡΠΌΠ°Π½ Π. ΠΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΠ΅ ΡΠ»Π΅Π΄ΠΎΠ²ΡΡ ΠΊΠΎΠ»ΠΈΡΠ΅ΡΡΠ² ΠΎΡΠ³Π°Π½ΠΈΡΠ΅ΡΠΊΠΈΡ Π²Π΅ΡΠ΅ΡΡΠ² / ΠΠ°ΠΉΠ΅ΡΠΌΠ°Π½ Π. Π.: ΠΠΈΡ, 1987. — 462 Ρ.
- ΠΡΠ΄Π½ΠΈΠΊΠΎΠ² Π. Π. ΠΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΠ΅ ΡΠ»Π΅Π΄ΠΎΠ²ΡΡ ΠΊΠΎΠ»ΠΈΡΠ΅ΡΡΠ² Π²Π΅ΡΠ΅ΡΡΠ² ΠΊΠ°ΠΊ ΠΏΡΠΎΠ±Π»Π΅ΠΌΠ° ΡΠΎΠ²ΡΠ΅ΠΌΠ΅Π½Π½ΠΎΠΉ Π°Π½Π°Π»ΠΈΡΠΈΡΠ΅ΡΠΊΠΎΠΉ Ρ ΠΈΠΌΠΈΠΈ / ΠΡΠ΄Π½ΠΈΠΊΠΎΠ² Π. Π. // Π₯ΠΈΠΌΠΈΡ. 2000. -28Ρ.
- ΠΠ³ΠΎΡΠΎΠ² A.M. Π’Π΅ΠΎΡΠΈΡ ΠΈ ΠΏΡΠ°ΠΊΡΠΈΠΊΠ° ΠΈΠΌΠΌΡΠ½ΠΎΡΠ΅ΡΠΌΠ΅Π½ΡΠ½ΠΎΠ³ΠΎ Π°Π½Π°Π»ΠΈΠ·Π° / ΠΠ³ΠΎΡΠΎΠ² A.M., ΠΡΠΈΠΏΠΎΠ² Π. Π., ΠΠ·Π°Π½ΡΠΈΠ΅Π² Π. Π., ΠΠ°Π²ΡΠΈΠ»ΠΎΠ²Π° Π. Π. Π.: ΠΡΡΡΠ°Ρ ΡΠΊΠΎΠ»Π°, 1991.-251 Ρ.
- ΠΠΌΠΌΡΠ½ΠΎΡΠ΅ΡΠΌΠ΅Π½ΡΠ½ΡΠΉ Π°Π½Π°Π»ΠΈΠ· // ΠΠΎΠ΄ ΡΠ΅Π΄. Π’. Π’. ΠΠ³ΠΎ, Π. ΠΠ΅Π½Ρ ΠΎΡΡ. Π.: ΠΠΈΡ, 1988.- 173−243 Ρ.
- ΠΠΎΠ½ΠΎΠ½Π΅Π½ΠΊΠΎ Π. Π. ΠΡΠΈΠΌΠ΅Π½Π΅Π½ΠΈΠ΅ ΡΠ²Π΅ΡΠ΄ΠΎΡΠ°Π·Π½ΠΎΠ³ΠΎ ΠΊΠΎΠ½ΠΊΡΡΠ΅Π½ΡΠ½ΠΎΠ³ΠΎ ΠΈΠΌΠΌΡΠ½ΠΎΡΠ΅ΡΠΌΠ΅Π½ΡΠ½ΠΎΠ³ΠΎ Π°Π½Π°Π»ΠΈΠ·Π° Π΄Π»Ρ ΠΎΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΡ ΡΡΠΌΠΎΠ½ΠΈΠ·ΠΈΠ½ΠΎΠ² Π³ΡΡΠΏΠΏΡ Π / ΠΠΎΠ½ΠΎΠ½Π΅Π½ΠΊΠΎ Π. Π., ΠΡΡΠΊΠΈΠ½ Π. Π., ΠΠΎΡΠΎΠ²Π° Π. Π., Π‘ΠΎΠ±ΠΎΠ»Π΅Π²Π° Π. Π. // ΠΡΠΈΠΊΠ»Π°Π΄Π½Π°Ρ Π±ΠΈΠΎΡ ΠΈΠΌΠΈΡ ΠΈ ΠΌΠΈΠΊΡΠΎΠ±ΠΈΠΎΠ»ΠΎΠ³ΠΈΡ. 1999. — Π’. 35. № 2. — Π‘. 206−211.
- ΠΠΎΠ»ΡΠΌΠ°Π½ Π―. ΠΠ°Π³Π»ΡΠ΄Π½Π°Ρ Π±ΠΈΠΎΡ ΠΈΠΌΠΈΡ / ΠΠΎΠ»ΡΠΌΠ°Π½ Π―., Π ΡΠΌ Π.-Π. Π.: ΠΠΈΡ., 2000.-366 Ρ.
- ΠΠΎΡΠ΅Π½ΠΌΠ°Π½ Π―.Π. ΠΠΊΡΡΡΠ°ΠΊΡΠΈΡ ΠΎΡΠ³Π°Π½ΠΈΡΠ΅ΡΠΊΠΈΡ ΡΠΎΠ΅Π΄ΠΈΠ½Π΅Π½ΠΈΠΉ / ΠΠΎΡΠ΅Π½ΠΌΠ°Π½ Π―. Π. // Π₯ΠΈΠΌΠΈΡ. 1997. -http://www.pereplet.ru/obrazovanie/stsoros/239.html
- ΠΠ°ΡΠΊΠΎΠ²ΡΠΊΠΈΠΉ Π.Π. ΠΠ΅ΠΊΠ°ΡΡΡΠ²Π΅Π½Π½ΡΠ΅ ΡΡΠ΅Π΄ΡΡΠ²Π°: Π 2 Ρ. / ΠΠ°ΡΠΊΠΎΠ²ΡΠΊΠΈΠΉ Π. Π. -14-Π΅ ΠΈΠ·Π΄. Π.: ΠΠΠ «ΠΠ·Π΄Π°ΡΠ΅Π»ΡΡΡΠ²ΠΎ ΠΠΎΠ²Π°Ρ ΠΠΎΠ»Π½Π°»: ΠΠ·Π΄Π°ΡΠ΅Π»Ρ Π‘. Π. ΠΠΈΠ²ΠΎΠ², 2001.-Π’. 2.-31 Ρ.
- ΠΡΠ°Π²ΠΈΠ»Π° ΠΏΠΎ ΠΎΡΠ³Π°Π½ΠΈΠ·Π°ΡΠΈΠΈ Π³ΠΎΡΡΠ΄Π°ΡΡΡΠ²Π΅Π½Π½ΠΎΠ³ΠΎ Π²Π΅ΡΠ΅ΡΠΈΠ½Π°ΡΠ½ΠΎΠ³ΠΎ Π½Π°Π΄Π·ΠΎΡΠ° Π·Π° ΡΠΎΠ΄Π΅ΡΠΆΠ°Π½ΠΈΠ΅ΠΌ Π³ΠΎΡΠΌΠΎΠ½Π°Π»ΡΠ½ΡΡ ΡΡΠΈΠΌΡΠ»ΡΡΠΎΡΠΎΠ² ΡΠΎΡΡΠ° ΠΈ ΡΠΈΡΠ΅ΠΎΡΡΠ°ΡΠΈΠΊΠΎΠ² Π² ΠΏΡΠΎΠ΄ΡΠΊΡΠΈΠΈ ΠΆΠΈΠ²ΠΎΡΠ½ΠΎΠ³ΠΎ ΠΏΡΠΎΠΈΡΡ ΠΎΠΆΠ΄Π΅Π½ΠΈΡ, № 604. 18.08. 1999.
- Π ΠΎΠ·Π΅Π½ Π.Π. ΠΡΠ½ΠΎΠ²Ρ ΡΠ½Π΄ΠΎΠΊΡΠΈΠ½ΠΎΠ»ΠΎΠ³ΠΈΠΈ / Π ΠΎΠ·Π΅Π½ Π.Π.- ΠΠΎΠ΄ ΡΠ΅Π΄. Π‘ΠΌΠΈΡΠ½ΠΎΠ²ΠΎΠΉ Π. Π. ΠΠ·Π΄Π°ΡΠ΅Π»ΡΡΡΠ²ΠΎ ΠΠΎΡΠΊΠΎΠ²ΡΠΊΠΎΠ³ΠΎ Π£Π½Π²Π΅ΡΡΡΠΈΡΠ΅ΡΠ°, 1994. — 115 Ρ.
- Π.Π‘Π°ΠΌΡΠΈΠ»ΠΎΠ² Π. Π. ΠΠΌΠΌΡΠ½ΠΎΡΠ΅ΡΠΌΠ΅Π½ΡΠ½ΡΠΉ Π°Π½Π°Π»ΠΈΠ· / Π‘Π°ΠΌΡΠΈΠ»ΠΎΠ² Π. Π. // Π‘ΠΎΡΠΎΡΠΎΠ²-ΡΠΊΠΈΠΉ ΠΆΡΡΠ½Π°Π», http://www.pereplet.ru/obrazovanie/stsoros/896.html. 1999.
- Π‘Π°Π½ΠΠΈΠ 2.3.2.1078−01, Π: Π€ΠΠ£Π «ΠΠ½ΡΠ΅ΡΠ‘ΠΠ». — 2002. — 155 Ρ.
- Π₯ΠΈΠΌΠΈΡΠ΅ΡΠΊΠ°Ρ ΠΈΠ½ΡΠΎΡΠΌΠ°ΡΠΈΠΎΠ½Π½Π°Ρ ΡΠ΅ΡΡ. Π€ΠΈΠ·ΠΈΡΠ΅ΡΠΊΠ°Ρ Ρ ΠΈΠΌΠΈΡ. ΠΠΎΡΠΊΠΎΠ²ΡΠΊΠΈΠΉ Π£Π½ΠΈΠ²Π΅ΡΡΠΈΡΠ΅Ρ // http://www.chem.msu.su/rus/olimpiad/russia/2006/reshvyb-phys.pdf
- Abraham G. Possible role of dexamethasone in sensitizing the beta-adrenergic receptor system in vivo in calves during concomitant treatment with clenbuterol / Abraham G., Gottschalk J., Ungemach F. // Pharmacology. -2004. Vol. 72 № 3. — P. 196−200.
- Abraham G. Solid-phase radioimmunoassay of estradiol-17 / Abraham G. // J Clin Endocrinol Metab. 1969. — Vol. 29. — P. 866−870.
- Allison A.C. Immunological adjuvants: Desirable properties and side-effects / Allison A.C., Byars N.E. // Molec. Immunol. 1991. — Vol. 28. — P. 297−384.
- Altman A. Immunomodifiers in vaccines / Altman A., Dixon F.J. // Advances in Veterinary Science and Comparative Medicine. 1989. — Vol. 33. — P. 301 343.
- Analitical strategies for residue analysis of veterinary drugs growth-promoting agents in food-producing animals a review / Stolker A.A.M., Brinkman U.A.Th. // J. Chromotogr. A. — 2005. — Vol. 1067. — P. 15−53.
- Antignac J.P. Analytical strategies for the direct mass spectrometric analysis of steroid and corticosteroid phase II metabolites / Antignac J.P., Brosseaud A., Gaudin-Hirret I., Andre F., Bizec B.L. // Steroids. 2005. — Vol. 70 № 3. — P. 205−216.
- Antignac J.P. Study of natural and artificial corticosteroid phase II metabolites in bovine urine using HPLC-MS/MS / Antignac J.P., Bizec B.L., Monteau F., Andre F. // Steroids. 2002. — Vol. 67. № 10. — P. 873−82.
- Asensio C. Role of glucocorticoids in the physiopathology of excessive fat deposition and insulin resistance / Asensio C., Muzzin P., Rohner-Jeanrenaud F. // Int. J. Obes. Relat. Metab. Disord. 2004. — Vol. 28 — P. 45−52.
- Australian Government, Dep. Of Agric., Fisheries and Forestry http://www.affa.gov.au/corporatedocs/publications/pdf/animalplanthealth/nrs/ international/ pigmrlsaug06. pdf
- Bennett B. A comparison of commercially available adjuvants for use in research / J. Immunol. Methods // Bennett Π., Check I.J., Olsen M.R., Hunter R.L.- 1992.-Vol. 153.-P. 31−40.
- Bevalot F. Analitical strategies for the screening of veterinary drugs and their residues / Bevalot F., Gaillard Y., Lhermitte M.A., Pepin G. J. // Chromatogr. Π.-2000.-Vol. 740.-P. 227.
- Caloni F. Determination of dexamethasone in milk of dairy cows by immuno-enzymatic assay / Caloni F., Belloli C., Crescenzo G., Ormas P., Archimbault P. // Vet. Hum. Toxicol. 2000. — Vol. 42. № 6 — p. 345−348.
- Carraway K.K. Carbodiimide modification of proteins / Carraway K.K., Kosland D.E. // Methods Enzymol. 1972. — Vol. 25. — P. 616.
- Cartmill J.A. Effect of dexamethasone, feeding time, and insulin infusion on leptin concentrations in stallions / Cartmill J.A., Thompson D.L., Storer W.A., Crowley J.C., Huff N.K., Waller C.A. // J. Anim. Sci. 2005. — Vol. 83.-P. 1875−1881.
- Cerni L. Dexamethasone and clenbuterol detection by enzyme immunoassay in bovine liver tissue: a new multiresidue extraction procedure / Cerni L., Bian-cotto G., Tondolo A., Bogoni P. // Food Agr. Immun. 1998. — Vol. 10 — P. 307−315.
- Clemons D.J. Evaluation of the subcutaneous chamber as an alternative to adjuvant immunization for antibody production in rabbits. / Clemons D.J., Besch-Williford C., Riley L.K. // Lab. Anim. Sci. 1992. — Vol. 42. — P. 307 311.
- Codex Alimentarius Commission. Joint FAO/WHO Food Standards programme, 1993.
- Codex Alimentarius Commission. Joint FAO/WHO Food Standards programme, 1998.
- Contaminants and Target Biological Matrices // School of Advanced Residue Analysis in Food. http://www. saraf-educ. org. 2003. — P. 51.
- Contiero L. Detection of dexamethasone residue in bovine livers and urines when used as growth promotoring agent / Contiero L., Neri Π., Giannetti L., Bagnati R., Pozza G., Angeletti R. // 5th Int. Symp. Hormone And Veterinary
- Drug Residue Analysis held at the Province of Antwerp House Antwerp, Belgium May 16−19, 2006. Abstract Book. Universiteit Gent. — 2006. — P. 71.
- Coons A.H. Demonstration of pneumoccocal antigen in tissues by use of fluorescent antibody / Coons A. H., Creech H.J., Jones R.N., Berliner E. // J. Immunol. 1942.-Vol. 45.-P. 159−170.
- Cooper P.D. The selective induction of different immune responses by vaccine adjuvants / Cooper P.D. // Strategies in Vaccine Design (by ed. Ada G.L.), Austin: R.G. Landes Company. 1994. — P. 125−158.
- Cooper P. D The adjuvanticity of Algammulin, a new vaccine adjuvant / Cooper P.D., McComb C., Steele EJ. // Vaccine. 1991. — Vol. 9 — P. 408−415.
- Courtheyn D. Misuse of growth promoters in livestock production / Courtheyn D., Vercammen J., Logghe M., Seghers H., De Wasch K., De Brander H. // Analytica Chimica Acta. 2002. — Vol. 473. — P. 71−82.
- Current Protocols in Immunology / By eds. Coligan J.E., Kruisbeek A.M., Margulies D.H., Shevach E.M., Strober W. New York: John Wiley & Sons, 1995.-P. 144.
- Czock D. Pharmacokinetics and Pharmacodynamics of Systemically Administered Glucocorticoids / Czock D., Keller F., Rasche F.M., Haussler U. // Clinical Pharmacokinetics 2005. — Vol. 44. β l. — p. 61−98.
- De Wasch K. Detection of corticosteroids in injection sites and cocktails by MSn / De Wasch K., De Brabander H., Courtheyn D., Van Peteghem C. // Analyst. 1998. — Vol. 123 № 12. — P. 2415−2422.
- Dighe K.K. A solid phase radioimmnoassay for plasma progesterone / Dighe K.K., Hunter W.M. // Biochem. J. 1974. — P.143,219−231.
- Dowling P. CgFARAD the Canadian Food Animal Residue Avoidance Database / Dowling P., Doucet M., Fortier S., Clark C. // www.canadianveterinarians.net /larounds.
- Dray S. Allotype suppression / Dray S. // Ontogeny of Acquired Immunity, A Ciba Foundation Symposium. Amsterdam: ASP, Elsevier, North Holland. -1971.-P. 87−103.
- Edwards R.W.H. The extraction and oxidation of urinary steroids conjugate / Edwards R.W.H., Kellie A.E., Wade A.P. // Memoirs of the Society for Endocrinology. 1953. — Vol. 2. — P. 53−63.
- EEC Council Regulation 508/99/CCE // Off. J. Eur. Commission, L60 of 9−3.1999.
- Eisen H.N. Variations in affinities of antibodies during the immune response / Eisen H.N., Siskind G.W. // Biochemistry. 1964. — Vol. 3. — P. 996−1008.
- ELISA and ELISPOT Products Handbook and Technical Guide // http://www.piercenet.com/files/ELISAHB 160 1158ptl. pdf
- ELISA Technical Bulletin No. 1 // http://www.corning.com/lifesciences/ technicalinformation/techdocs/elisal.pdf
- ELISA Technical Bulletin No. 2 // http://www.corning.com/lifesciences/ technicalinformation/techdocs/elisa2.pdf
- ELISA Technical Bulletin No. 5 // http://www.corning.com/lifesciences/ technicalinformation/techdocs/elisa5.pdf
- Elliott C. Screening Methods / Elliott C. // School of Advanced Residue Analysis in Food. http://www. saraf-educ. org. 2003.
- English J. The metabolism of dexamethasone in the rat effect of phenytoin / English J., Chakraborty J., Marks V. // J. Steroid Biochem. — 1975. — Vol. 6. -P. 65−68.
- Engvall E. Enzyme-linked immunosorbent assay (ELISA): Quantitative assay of immuno-globulin G / Engvall E., Perlmann P.O. // Immunochemistry. -1971.-Vol. 8.-P. 871−875.
- Enzyme-irnmunoassay / By ed Maggio E.T. Boca Raton, FL: CRC Press. -1980.-P. 105−34.
- Erlanger B.F. The preparation of antigenic hapten-carrier conjugates: A survey / Erlanger B.F. // Methods Enzymol. 1980. — Vol. 70. — P. 85−104.
- Erlanger B.F. Principles and methods for the preparation of drug protein conjugates for immunological studies / Erlanger B.F. // Pharmacol. Rev. 1973. -Vol. 25.-P. 271−280.
- Euro-Diagnostica B.V. Corticosteroid EIA, The Netherland // 5081CORlp6.08.05
- European Medicines Agency Veterinary Medicines and Inspections // http://www.emea.eu.int/pdfs/vet/mrls/8 7403en.pdf. London. — 2004.
- Fanger M.W. The oligosaccharide units of rabbit immunoglobulin G. Asymmetric attachment of C2-oligosaccharide / Fanger M.W., Smyth D.G. // Bio-chem. J. 1972. — Vol. 127. — P. 767−774.
- Fearon D.T. The CD 19/CR2/TAPA-1 complex of Π lymphocytes: Linking natural to acquired immunity / Fearon D.T., Carter R.H. // Annu. Rev. Immunol. 1995.-Vol. 13.-P. 127−149.
- Food and Agriculture organization of the United Nation. 2006. -www.fao.org/docrep/meeting/005/X0203E/x0203e0e.htm
- Fuentes M. Optimization of the modification of carrier proteins with aminated haptens / Fuentes M., Palomo J. M., Mateo C., Venteo A., Sanz A., Fernandez-Lafuente R., Guisan J.M. // Journal of Immunological Methods. 2005. — Vol. 307. № 1−2.-P. 144−149.
- Gaignage P. Dexamethasone bovine pharmacokinetics / Gaignage P., Lognay G., Bosson D., Vertongen D., Dreze P., Marlier M., Severin M. // Eur. J. Drug. Metab. Pharmacokinet. 1991. — Vol. 16 № 3. — P. 219−221.
- Goidl E.A. The effect of antigen dose and time after immunization on the amount and affinity of anti-hapten antibody / Goidl E.A., Paul W.E., Siskind G.W., Benacerraf B. // J. Immunol. 1968. — Vol. 100. — P. 371−375.
- Goudie R.B. A simple method for producing antibody specific to a single selected diffusible antigen / Goudie R.B., Home C.H.W., Wilkinson P.C. // Lancet. 1966. — Vol. 2. — P. 1224−1226.
- Great Plains Veterinary Educational Center // http://gpvec.unl.edu/files/feedlot/internettempfiles/ResidueInfo-MRL/MRLVetDrugsJpEuUSJune2006DG-Pnt.htm.
- Greco D.S. Dexamethasone pharmacokinetics in clinically normal dogs during low- and high-dose dexamethasone suppression testing / Greco D.S., Brown S.A., Gauze J.J., Weise D.W., Buck J.M. // Am. J. Vet. Res. 1993. — Vol. 54. № 4.-P. 580−585.
- Grossman C.J. The regulation of the immune system by sex steroids / Grossman C.J. // Endocr. Rev. 1984. — Vol. 5. — P. 435−455.
- Grossman C.J. Possible underlying mechanisms of sexual dimorphism in the immune response, fact and hypothesis / Grossman C.J. // J. Steroid. Biochem. -1989.-Vol. 34.-P. 241−251.
- Haasnoot W. Residue Analysis in Food: Principles and Applications. Immunochemical and receptor technologies / Haasnoot W., Schilt R.- By ed. O’Keeffe M. Harwood Academic Publishers, The Netherlands, 1999. — P. 109−144.
- Hanly W.C. Review of Polyclonal Antibody Production Procedures in Mammals and Poultry / Hanly W. C., Artwohl J.E., Bennett T.B. // ILAR Journal. -1995-Vol. 37. № 3.
- Hansen D.K. Pharmacokinetic considerations of dexamethasone-induced developmental toxicity in rats / Hansen D.K., LaBorde J.B., Wall K.S., Holson R.R., Young J.F. // Toxicological Sciences. 1999. — Vol. 48. — P. 230−239.
- Harlow, E. Antibodies: A Laboratory Manual / Harlow E., Lane D. // Cold Spring Harbor, N.Y. 1988. — P. 215.
- Herbert W.J. The mode of action of mineral-oil emulsion adjuvants on antibody production in mice / Herbert W.J. // Immunology. 1968. — Vol. 14. — P. 301−318.
- Hirokawa K. Understanding the mechanism of the age-change of thymic function to promote T cell differentiation / Hirokawa K., Utsuyama M., Kasai M., Kurashima C., Ishimima S., Zeng Y-X. // Immunol. Lett. 1994. — Vol. 40. -P. 269−277.
- Horbett T.A. Proteins at Interfaces: An overview, in Proteins at Interfaces II: Fundamentals and Applications (by ed. Horbettand T.A., Brash J.L.) / Horbett T.A., Brash J.L. // ACS Symposium Series, ACS Books, Washington, D.C. -1995.-P. 1−23.
- Horbett T.A. The role of adsorbed adhesion proteins in cellural recognition of biomaterials / Horbett T.A. // BMES Bulletin. 1999. — Vol. 23 № 2. — P. 5−9.
- Hu J-G. Studies on the optimal immunization schedule of the mouse as an experimental animal. The effect of antigen dose and adjuvant type / ΠΠΈ J-G., Ide A., Yokoyama Π’., Kitagawa T. // Chem. Pharm. Bull. 1989a. — Vol. 37. — P. 3042−3046.
- Huetos O. Determination of dexamethasone in feed by TLC and HPLC / Hue-tos O., Ramos M., Martin de Pozuelo M., San Andres M., Reuvers M. // Analyst. 1999.-Vol. 124. № 11. -P. 1583−1587.
- Hum B.A.L. Production of reagent antibodies / Hum B.A.L., Chantler S.M. // Methods Enzymol. 1980. — Vol. 70. — P. 104−142.
- Introduction of antibody Enzyme-Linked Immunosorbent assay // http://www.chemicon.com/resource/ANT101/a2C.asp
- Janeway C.A.Jr. Immunobiology. / Janeway C.A.Jr., Travers P. New York: Garland Publishing Inc. — 1994. — IX. — P. 152.
- Jones G.L. Peptide vaccines derived from a malarial surface antigen: Effects of dose and adjuvants on immunogenicity / Jones G.L., Spencer L., Lord R., Mol-lard R., Pye D. // Saul. Immunol. Lett. 1990.- Vol. 24. — P. 253−260.
- Kenney J.S. Influence of adjuvants on the quantity, affinity, isotype and epitope specificity of murine antibodies / Kenney J.S., Hughes B.W., Masada M.P., Allison A.C.//J. Immunol. Methods- 1989.-Vol. 121.-P. 157−166.
- Kundu N. Production of antisera against contraceptive steroids / Kundu N., Keenan S, Slaunwhite W.R. // Steroids. 1977. — Vol .30. — P. 85−96.
- Laboratory techniques in biochemistry and molecular biology. Practice and theory of enzyme immunoassay / By eds. Burbon R.H., Knippenberg van P.H. Elsevier, Amsterdam. — 1985. — P. 1−549.
- Leish Z. Studies on intravenously infused dexamethasone in sheep / Leish Z., Panaretto B. A. // Aust. J. biol. Sci. 1978. -Vol. 31. — P. 373−383.
- Luo Y. Simultaneous analysis of twenty-one glucocorticoids in equine plasma by liquid chromatography/tandem mass spectrometry / Luo Y., Uboho Π‘. E., Soma L. R., Guan F. Y., Rudy J. A., Tsang D. S. // J. Agric. Food Chem. 2003. -Vol. 51.-P. 326−30.
- Maletto B. Aging: The cellular immune response against autologous and foreign antigens is affected before the humoral response / Maletto, Π., Pistoresi-Palencia M.C., Gruppi A. // Immunol. Lett. 1994. — Vol. 40. — P. 243−250.
- Mallinson E. T. Determination of Dexamethasone in Liver and Muscle by Liquid Chromatography and Gas ChromatographyMass Spectrometry / Mallinson E. Π’., Dreas J. S., Wilson R. Π’., Henry A. C. // J. Agric. food Chem.1995.-Vol. 43.-P. 140−145.
- Manne S. Kinetics of antigen-antibody reactions at solid-liquid interfaces / Manne S., Nygren H. // Journal of Immunological Methods 1988. — Vol. 113. -P. 3−15.
- Maurer P.H. Protein and polypeptides as antigens / Maurer P.H., Callahan H.J. // Methods Enzymol. 1980. — Vol. 70. — P. 49−70.
- Mayumi S. Correlation between plasma leptin concentration and body fat content in dogs / Mayumi S., Nakadomo F., Honjoh Π’., Ishioka S., Saito M.// Am. J. Vet. Res. 2002. — Vol. 63. — P. 7−10.
- MedecineNet // http://www.medicinenet.com/elisatests/article.htm
- McCoy K.L. Tolerance defects in New Zealand Black and New Zealand Black and New Zealand White F1 mice / McCoy K.L., Kendrick L., Chused T.M. // J. Immunol. 1986.-Vol. 136.-P. 1217−1222.
- Miller R.A. Aging and immune function: Cellular and biochemical analyses / Miller R.A. // Exp. Gerontology. 1992. — Vol. 29. — P. 21−25.
- Mostl E. Measurement of glucocorticoid metabolite concentrations in faeces of domestic livestock / Mostl E., Messmann S., Bagu E., Robia C., Palme R. // Zentralbl Veterinarmed A. 1999. — Vol. 46. — P. 621−631.
- Nisbet A.D. The complete amino-acid sequence of hen ovalbumin / Nisbet A.D., Saundry R.H., Moir A.J., Fothergill L.A., Fothergill J.E. // European Journal of Biochemistry. 1981 -Vol. 115.-P. 335−345.
- Oka H. Chemical analysis for antibiotics used in agriculture / By eds. Oka H., Nakazawa H., Harada K-I., Macnel J.D. AOAC international, VA. — 1995. -P. 215.
- O’Keeffe M.J. Supercritical fluid extraction of veterinary drug residues from meat / O’Keeffe M.J., O’Keeffe M. // The national food center. Research report No 19. Dublin. 1999 — ISBN I 841 700 762. — P. 18.
- Official Jornal of the European Communites L221, 8−36, Commission Decision (2002/657/EC) of 12 August 2002. Brussels, Belgium, 2002.
- Paganelli R. Humoral immunity in aging /Paganelli, R., Scala E., Quinti I., Ansotegui I.J. // Aging Clin. Exp. Res. 1994. Vol.6. — P. 143−150.
- Pagano G. An in vivo and in vitro study of the mechanism of prednisone-induced insulin resistance in healthy subjects / Pagano G., Cavallo-Perin P., Cassader M., et al. // J Clin Invest. 1983. — Vol. 72. — P. 1814−1820.
- Peets E.A. Plasma binding of betamethasone-3H, dexamethasone-3H, and Cortisol-14C a comparative study / Peets E.A., Stam M., Symcowicz C. // Bio-chem. Pharmacol. — 1969.-Vol. 18.-P. 1655−1663.
- Passingham B. Application of high-performance liquid chromatography to the measurement of Cortisol secretion rate / Passingham B. J., Barton R. // Journal of Chromatography: Biomedical Applications. 1987. — Vol. 416. — P. 25−35.
- Pham-Huu-Trung M.T. A direct determination of plasma aldosterone / Pham-Huu-Trung M.T., Corvol P. // Steroids. 1974. — Vol. 24. — P.587−598.
- Philippe J. Cyclic adenosine monophosphate prevents the glucocorticoid-mediated inhibition of insulin gene expression in rodent islet cells / Philippe J., Giordano E., Gjinovci A., Meda P. // J. Clin. Invest. 1992. — Vol. 90. — P. 2228−2233.
- Ramos M. Determination of dimetridazole residues in bovine tissue by liquid chromatography / Ramos M., Aranda A., Reuvers Th., Jimenez R. // Analytica Chimica Acta. 1993. — Vol. 275. — P. 317−321.
- Reding J. Dexamethasone and flumethasone residues in milk of intramuscularly dosed cows / Reding J., Sahin A., Schlatter J., Naegeli H. // J. Vet. Pharmacol. Ther. 1997. — Vol. 20(3). — P. 198−203.
- Report for 2004 on the results of residue monitoring in food of animal origin in the Member States // European Commission Health And Consumer Protection
- Derictorate-General, Annex I (SANCO/3400/2005). http://ec.europa.eu/food/food/chemicalsafety/residues/workdoc2004en.pdf. -2004.
- Report for 2005 on the results of residue monitoring in food of animal origin in the Member States // European Commission Health And Consumer Protection Derictorate-General, Annex I (SANCO/3635/2006. http://ec.europa.eu/)
- Rice M.J. The metabolism of dexamethasone in the rat / Rice M.J. Tredger J.M., Chakraborty J., Parke D.V. // Biochem. Soc. Transact., 53rd Meeting, Bristol. 1974.-Vol. 2.-P. 107−109.
- Rubenstein K.E. Homogeneous enzyme immunoassay. A new immunochemical technique / Rubenstein K.E., Schneider R.S., Ullman E.F. // Biochem. Bio-phys. Res. Commun. 1972. — Vol. 47. — P. 846−51.
- Schnibbe T. Effectiveness of Different Common Carriers for the Immuno-genicity of Synthetic Peptides. 2000. — http://www.diss.fu-berlin.de/2000/148/indexe.html
- Scippo M.L. Primary Extraction Technologies in: Residue analysis in Food -Principles and Applications / Scippo M.L., Maghuin-Rogister G.- by ed. O’Keefe M. Harwood Academic Publishers, Amsterdam. — 2000.
- Scippo M.L. Detection of illegal growth promoters in biological samples using receptor binding assays / Scippo M.L., Weerdt C.V.D., Willemsen P., Francois
- J.-M., Rentier-Delrue F., Muller M., Martial J.A., Maghuin-Rogister G. // Analytica Chimica Acta. 2002. — Vol. 473. № 1. — P. 135−141.
- Sela M. Studies on the chemical basis of the antigenicity of proteins. 1. Antigenicity of polypeptidyl gelatins / Sela M., Arnon R. // Biochem J. 1960. -Vol. 75.-P. 91−102.
- Seuter E. Metabolism of systematically given corticosteroids / Seuter E. // Dermatologica. 1975-Vol. 151.-P. 129−134.
- Singh H. In vitro and in vivo genotoxicity evaluation of hormonal drugs. II. Dexamethasone / Singh H., Singh J.R., Dhillon V.S., Bali D., Paul H. // Mutat Res. 1994. — Vol. 308. — P. 89−97.
- Siskind, G.W. Studies on the control of antibody synthesis: II. Effect of antigen dose and of suppression by passive antibody on the affinity of antibody synthesized / Siskind, G.W., Dunn P., and Walker J.G. // J. Exp. Med. 1968. -Vol. 127.-P. 55−66.
- Snapper C.M. Fundamental Immunology. Immunoglobulin class switching / Snapper, C.M., Finkelman F.D.- dy ed. Paul W.E. New York: Raven Press., 1993.-P. 837−863.
- Strategies in Vaccine Design. The generation and maintenance of antibody and Π cell memory: The role of retained antigen and follicular dendritic cells / by ed. Ada G.L. Austin Burton Tex.: R.G. Landes Company, 1994. — P. 35−49.
- Stills, H.F. The Biology of the Laboratory Rabbit. Polyclonal antibody production / Stills, H.F. // By eds. Manning P.J., Ringler D.H., Newcomer C.E. San Diego: Academic Press., 1994. — P. 435−448.
- Stills, H.F. The use of Freund’s complete adjuvant / Stills, H.F., Bailey M.Q. // Lab. Anim. (US) -1991. Vol. 20. — P. 25−30.
- Stolker A. A.M. Analysis of corticosteroids / Stolker A. A.M., Schwillens P.L., Ginkel L.A., Brinkman U.A.T. // J. Chromotogr. A. 2000. — Vol. 893 № 1. — P. 55−67.
- Surface Characterization of Biomaterials, Book Review / by ed. Ratner B. D. -Elsevier Science Publishers, 1988.-P. 124.
- Tarantola M. Effects of low doses of dexamethasone on productive traits and meat quality of veal calves / Tarantola M., Schiavone A., Preziuso G., Russo C., Biolatti Π., Bergero D. // Animal Science. 2004. — Vol. 79. — P. 93−98.
- Tecna S.r.l. Kit ELISA per corticosteroidi, Italy // Cat N FA679.
- The Europen Agency for the Evaluation of Medicinal Products, Veterinary Medicines Evaluation Unit, Commettee for Veterinary Medicinal Products, Approach Towards Harmonization of Withdrawal Periods EMEA/CVMP/36/95.
- The Extra Pharmacopoeia / By ed. Reyonolds J.E.F. Martindale: The Pharmaceutical Press, London, 1989. — P. 1895.
- The Japan Food Chemical Research Foundation http://www.m5.ws001 .squarestart.ne.jp/foundation/search.html
- Touma C. Measuring Fecal Glucocorticoid Metabolites in Mammals and Birds: The Importance of Validation Ann / Touma C., Palme R. // N.Y. Acad. Sci. -2005.-Vol. 1046.-P. 54−74.
- Toutain P.L. Dexamethasone in cattle: pharmacokinetics and action on the adrenal gland / Toutain P.L., Brandon R.A., Alvinerie M., Garcia-Villar R., Ruckebusch Y // J. Vet. Pharmacol. Ther. 1982. — Vol. 5. — P. 33−43.
- Toutain P.L. Pharmacokinetics of dexamethasone and its effect on adrenal gland function in the dog / Toutain P.L., Alvinerie M., Ruckebusch Y. // Am. J. Vet. Res. 1983. — Vol. 44. — P. 212−217.
- Toutain P.L. Dexamethasone and prednisolone in the horse: pharmacokinetics and action on the adrenal gland / Toutain P.L., Brandon R.A., de Pomyers H., Alvinerie M., Baggot J.D. // Am. J. Vet. Res. 1984. — Vol.45. — P. 1750−1756.
- Tsuei S.E. Disposition of synthetic glucocorticoids I. Pharmacokinetics of dexamethasone in healthy adults / Tsuei S.E., Moore R. G., Ashley J. J., McBride W.G. // Journal of Pharmacokinetics and Pharmacodynamics. 1979. -Vol. 7№ 3.
- U.S. Government Printing Office // http://www.access.gpo.gov/nara/cfr/waisidx06/21cfr55606.html.
- Vaccine Biotechnology / By eds. Bittle J.L., Murphy F.L. New York: Academic Press. — 1999.-P. 151.
- Van den Hauwe 0. Simultaneous determination of betamethasone and dexamethasone residues in bovine liver by liquid chromatography/tandem mass spectrometry / Van den Hauwe 0., Castro Perez J., Claereboudt J., Van Peteghem C.
- Rapid Communications in Mass Spectrometry. 2002. -Vol. 15. — P. 857 -861.
- Varma D.R. Anti-inflammatory and ulcerogenic effects and pharmacokinetics of dexamethasone in protein-deficient rats / Varma D.R., Mulay S. // J. Phar-maco. Exp. Ther. 1980. — Vol. 214. — P. 197−202.
- Vranic M.L. Estimation the withdrawl period for veterinary drugs used in food producing animals / Vranic M.L., Marangunich L., Fernandez Courel H., Fernandez Saurez A. // Analytica Chimica Acta. 2003. — Vol. 483. — P. 251−257.
- Walker B.E. Induction of cleft palate in rabbits by several glucocorticoids / Walker B.E. // Proc. Soc. Exp. Biol. Med. 1967. — Vol. 125. — P. 1281−1284.
- Walker B.E. Induction of cleft palate in rats with anti-inflammatory drugs / Walker B.E. // Teratology. 1971. — Vol. 4. — P. 39−42.
- Warr G.W. IgY: Clues to the origins of modern antibodies / Warr G.W., Mator K.E., Higgins D.A. // Immunol. Today. 1995. — Vol. 16. — P. 392−398.
- Warren, H.S. Future prospects for vaccine adjuvants / Warren, H.S., Chedid L.A. // CRC Critical Reviews Immunol. 1988. — Vol. 8. — P. 83−101.
- Weller Π’.Π. Fluorescent antibody studies with agents of varicella and herpes zoster, propagated in vitro / Weller Π’.Π., Coons A.H. // Proc. Soc. Exp. Biol. Med. 1954. — Vol. 86. — P. 789−794.
- Wikipedia on-line encyclopedia//http://146.107.217.178/lab/alogps/start.html.
- Wikipedia on-line encyclopedia // http://en.wikipedia.org/wiki/Corticosteroids.
- Wikipedia on-line encyclopedia // http://ibmlc2.chem.uga.edu/sparc/
- Wikipedia on-line encyclopedia // http://en.wikipedia.org/wiki/ELISA.
- Wikipedia on-line encyclopedia // http://pubchem.ncbi.nlm.nih.gov/search/
- Wikipedia on-line encyclopedia // http://en.wikipedia.org/wiki/Liquid-liquidextraction.
- Wikipedia on-line encyclopedia // http://en.wikipedia.org/wiki/Polarsurfacearea.
- Wikipedia on-line encyclopedia // http://en.wikipedia.org/wiki/Steroid.
- Wisdom G.B. Peptide Antigens / Wisdom G.B. // Oxford University Press, Oxford.- 1995.
- Woodard, L.F. Bacterial Vaccines. Surface chemistry and classification of vaccine adjuvants and vehicles / Woodard, L.F.- by ed. A. Mizrahi. New York: Alan R. Liss., 1990. — P. 286−306.