Механизмы иммунопатогенеза ВИЧ-инфекции и вирусного гепатита С на оригинальных моделях гуманизированных мышей
Диссертация
В последние десятилетия медицинским работникам различных специальностей приходится иметь дело с особым видом инфекционных заболеваний. Данные инфекции, как правило вирусной этиологии, не вызывают в большинстве случаев яркой клинической симптоматики во время и непосредственно после инфицирования, но их возбудители, проникая в клетки и реплицируясь в них, приводят к длительной персистенции… Читать ещё >
Содержание
- Глава I. ОБЗОР ЛИТЕРАТУРЫ
- Глава II. МАТЕРИАЛЫ И МЕТОДЫ
- Глава III.
- Создание адекватных гуманизированных мышиных моделей системной инфекции, позволяющих изучать патогенез ВИЧ инфекции
- Глава IV.
- Изучения патогенеза ВИЧ инфекции на ДНО-hu модели гуманизированных мышей
- Глава V.
- Создание мышиной модели для изучения патогенеза и терапевтических подходов гепатропных инфекций
- Глава VI.
- Разработка иммуномодулирующей таргетной вакцинотерапии тяжелых инфекционных заболеваний
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