Влияние факторов экзогенного и эндогенного происхождения на функциональную активность гемопоэтической стволовой клетки в норме и при аутоиммунной патологии
![Диссертация: Влияние факторов экзогенного и эндогенного происхождения на функциональную активность гемопоэтической стволовой клетки в норме и при аутоиммунной патологии](https://westud.ru/work/3635948/cover.png)
Диссертация
Н7 и ролипрам стимулируют апоптоз CD34+ клеток мышей MRL-lpr/lpr, при этом Н7 подавляет эритроидную дифференцировку ГСК мышей MRL-lpr/lpr in vitro. Вортманнин подавляет эритроидную дифференцировку, не влияя на апоптоз CD34+ клеток. В условиях трансплантации ККМ, инкубированных с препаратами, Н7 подавляет кроветворение в костном мозге реципиентов, вортманнин и ролипрам не оказывают влияния на этот… Читать ещё >
Содержание
- ЧАСТЬ I. ОБЗОР ЛИТЕРАТУРЫ
- ГЛАВА 1. Трансплантация ГСК в клинической практике
- 1. 1. Источники ГСК для трансплантации в клинической практике
- 1. 2. Популяционная структура ГСК
- ГЛАВА 2. Функциональная активность ГСК
- 2. 1. Функциональные характеристики ГСК
- 2. 2. Регуляция самоподдержания ГСК
- 2. 3. ГСК и ее микроокружение. Миграция и хоминг ГСК
- 2. 3. 1. Роль гиалуроновой кислоты в гемопоэзе
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