Патогенетическое и клиническое значение плазмоцитоидных дендритных клеток при вирусном гепатите С у детей и взрослых
Диссертация
ПДК являются отдельным видом клеток крови, близким по развитию и генетическому профилю общим дендритным клеткам, впервые описанным R.M. Steinman и Z.A. Cohn в 1973 году. ПДК были впервые открыты Celia М., Jarrosay D., Fecchetti F. et al- Siegal F.P., Ka-dowaki N., Shodell M. et al в 1999 году. Они имеют костномозговое происхождение и развиваются из стволовой клетки через ряд предшественников… Читать ещё >
Содержание
- СПИСОК СОКРАЩЕНИЙ ЧАСТЬ I. ОБЗОР ЛИТЕРАТУРЫ
- ГЛАВА 1. ПЛАЗМОЦИТОИДНЫЕ ДЕНДРИТНЫЕ КЛЕТКИ И
- ИХ РОЛЬ В ОРГАНИЗМЕ ЧЕЛОВЕКА
- ГЛАВА 2. ПЛАЗМОЦИТОИДНЫЕ ДЕНДРИТНЫЕ КЛЕТКИ В
- ПАТОГЕНЕЗЕ ВИРУСНОГО ГЕПАТИТА С
- ЧАСТЬ II. СОБСТВЕННЫЕ ИССЛЕДОВАНИЯ
- ГЛАВА 3. ПАЦИЕНТЫ И МЕТОДЫ
- 3. 1. Клиническая характеристика обследованных
- 3. 1. 1. Состав всех обследованных
- 3. 1. 2. Клиническая характеристика больных
- 3. 2. Методы обследования 50 3.2.1 Базовые методы обследования
- 3. 2. 2. Методы тестирования маркёров вируса гепатита С
- 3. 2. 3. Дополнительные методы обследования
- 3. 2. 4. Специальные методы исследования 51 3.2.5 Дополнительные специальные методы
- 3. 2. 6. Дизайн исследования
- 3. 2. 7. Статистическая обработка результатов
- 3. 1. Клиническая характеристика обследованных
- 4. 1. Количественные показатели ПДК у здоровых детей и взрослых
- 4. 1. 1. Количественные показатели ПДК у больных ХГС и здоровых
- 4. 2. Связь количественных показателей ПДК с клинико-лабораторными параметрами у детей, больных ХГС
- 4. 3. Связь количественных показателей ПДК с клинико-лабораторными параметрами у взрослых, больных ХГС
- 4. 4. Сравнительная количественная характеристика ПДК у детей и взрослых, больных ХГС
- 5. 1. Функциональное состояние ПДК у здоровых детей и взрослых
- 5. 2. Функциональное состояние ПДК у больных ХГС детей и взрослых
- 5. 2. 1. Связь функционального состояния ПДК с клинико-лабораторными параметрами у детей, больных ХГС
- 5. 3. Связь функционального состояния ПДК с клинико-лабораторными параметрами у взрослых, больных ХГС
- 5. 4. Сравнительный анализ функционального состояния ПДК у детей и взрослых, больных ХГС
- 6. 1. Соотношение количественных показателей ПДК и ПВТ у детей
- 6. 2. Соотношение количественных показателей ПДК и ПВТ у взрослых
- 6. 3. Сравнительная характеристика количественных показателей ПДК и ПВТ у детей и взрослых, больных ХГС
- 6. 4. Соотношение функциональных показателей ПДК и ПВТ у детей, больных ХГС
- 6. 5. Соотношение функциональных показателей ПДК и ПВТ у взрослых
- 6. 6. Сравнительная характеристика функциональных показателей ПДК и ПВТ у детей и взрослых
- 6. 7. Соотношение функциональных показателей ПДК и эффективности ПВТ у детей
- 6. 8. Соотношение функциональных показателей ПДК и эффективности ПВТ у взрослых
6.9 Соотношение показателей ПДК с ПВТ у пациентов с отсутствием вирусной репликации (с авиремией). б.Ю.Новый тест для прогнозирования ответа на противовирусную терапию (ПВТ) при хроническом гепатите С (ХГС)
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