Клонирование генов полипептидных нейротоксинов яда членистоногих
Диссертация
Яд членистоногих, как правило, состоит из большого количества низкомолекулярных белковых компонентов, которые токсичны для различных классов животных, включая человека. Для отдельных токсичных компонентов, выделенных из яда членистоногих, характерна таксоспецифичность действия. Так, например, из яда скорпионов «Старого» и «Нового Света» выделены токсины, избирательно воздействующие… Читать ещё >
Содержание
- 1. ВВЕДЕНИЕ
- 2. ЛИТЕРАТУРНЫЙ ОБЗОР МОЛЕКУЛЯРНАЯ ОРГАНИЗАЦИЯ ТОКСИНОВ ПАУКООБРАЗНЫХ"
- 2. 1. Введение
- 2. 2. Анализ структуры сигнальных пептидов и 3'- нетранслируемых последовательностей кДНК, кодирующих токсины скорпионов
- 2. 3. Анализ кодирующей последовательности кДНК
- 2. 4. Клонирование геномной ДНК
- 2. 5. Сравнительный анализ аминокислотных последовательностей токсинов скорпионов, выведенных на основе последовательности их кДНК
- 2. 6. Семейства гомологичных токсинов из яда паукообразных
- 2. 7. Пространственное строение токсинов пауков
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