Одночастичные и коллективные оптические свойства золотых нанооболочек в связи с биомедицинскими применениями
Диссертация
Для успешных in vivo применений золотых наночастиц в биофизике и биомедицине, включая визуализацию и фототермолиз раковых клеток, необходимо сочетание многих факторов. С медицинской точки зрения принципиальной является проблема биораспределения и биотоксичности используемых наночастиц. В частности, нанометровые частицы способны накапливаться и долго удерживаться в селезенке, почках и, особенно… Читать ещё >
Содержание
- Глава 1. Обзор литературы и постановка задач исследования
- 1. 1. Методы получения металлических нанооболочек
- 1. 1. 1. Золотые нанооболочки на ядрах из двуокиси кремния
- 1. 1. 2. Другие виды нанооболочек
- 1. 2. Оптические свойства металлических нанооболочек
- 1. 2. 1. Зависимость оптических свойств нанооболочек от размера и структуры
- 1. 2. 2. Зависимость оптических свойств нанооболочек от шероховатости поверхности и показателя преломления окружающей среды
- 1. 2. 3. Коллективные оптические свойства золотых нанооболочек
- 1. 2. 4. Методы компьютерного моделирования оптических свойств золотых нанооболочек
- 1. 3. Использование нанооболочек в нанобиотехнологии
- 1. 3. 1. Визуализация и контрастирование
- 1. 3. 2. Фототермическая терапия
- 1. 3. 3. Комбинационное (рамановское) рассеяние света
- 1. 4. Постановка задач исследования
- 1. 1. Методы получения металлических нанооболочек
- Глава 2. Определение размера, концентрации и показателя преломления наночастиц оксида кремния методом спектротурбидиметрии
- 2. 1. Теория
- 2. 2. Экспериментальное определение размера, концентрации и показателя преломления наночастиц оксида кремния
- 2. 2. 1. Материалы и методы
- 2. 2. 2. Результаты и обсуждение
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