Π Π΅Π³ΡΠ»ΡΡΠΈΡ ΡΠΊΡΠΏΡΠ΅ΡΡΠΈΠΈ Π³Π΅Π½ΠΎΠ² ΠΏΠΎΡΠΎΡΠΎΡΠΌΠΈΡΡΡΡΠΈΡ ΡΠΎΠΊΡΠΈΠ½ΠΎΠ² B. cereus
ΠΠΈΡΡΠ΅ΡΡΠ°ΡΠΈΡ
ΠΠΏΡΠ΅Π΄Π΅Π»Π΅Π½Ρ ΡΠ°ΡΡΠΎΡΡ Π²ΡΡΡΠ΅ΡΠ°Π΅ΠΌΠΎΡΡΠΈ Π³Π΅Π½ΠΎΠ² cytK, hlyll, hlyllR ΡΡΠ΅Π΄ΠΈ 40 ΠΏΡΠΈΡΠΎΠ΄Π½ΡΡ ΠΈΠ·ΠΎΠ»ΡΡΠΎΠ² Π±Π°ΠΊΡΠ΅ΡΠΈΠΉ Π³ΡΡΠΏΠΏΡ Bacillus cereus ΠΈ ΠΎΠΏΠΈΡΠ°Π½ ΠΏΠΎΠ»ΠΈΠΌΠΎΡΡΠΈΠ·ΠΌ Π³Π΅Π½ΠΎΠ² ΡΠΎΠΊΡΠΈΠ½ΠΎΠ². ΠΠΎΠΊΠ°Π·Π°Π½ΠΎ, ΡΡΠΎ Π±Π»ΠΈΠ·ΠΊΠΈΠΌΠΈ ΠΠΠ Π€ ΡΠΈΠΏΠ°ΠΌΠΈ Π³Π΅Π½ΠΎΠ² ΠΎΠ±Π»Π°Π΄Π°ΡΡ ΡΡΠ°ΠΌΠΌΡ ΠΈΠ· ΠΎΠ΄Π½ΠΈΡ ΠΈ ΡΠ΅Ρ ΠΆΠ΅ ΡΠΈΠ½Π³Π΅ΡΠΏΡΠΈΠ½ΡΠ½ΡΡ ΠΊΠ»Π°ΡΡΠ΅ΡΠΎΠ². ΠΠ΅Π½ hlyllR Π²ΡΡΡΠ΅ΡΠ°Π΅ΡΡΡ ΡΠΎΠ»ΡΠΊΠΎ ΡΠΎΠ²ΠΌΠ΅ΡΡΠ½ΠΎ Ρ Π³Π΅Π½ΠΎΠΌ Π³Π΅ΠΌΠΎΠ»ΠΈΠ·ΠΈΠ½Π° II. Π¦Π΅Π»ΡΡ Π΄Π°Π½Π½ΠΎΠΉ ΡΠ°Π±ΠΎΡΡ ΡΠ²Π»ΡΠ»ΠΎΡΡ ΠΈΠ·ΡΡΠ΅Π½ΠΈΠ΅ ΠΎΡΠΎΠ±Π΅Π½Π½ΠΎΡΡΠ΅ΠΉ ΠΌΠ΅Ρ Π°Π½ΠΈΠ·ΠΌΠ° ΡΠ΅Π³ΡΠ»ΡΡΠΈΠΈ Π³Π΅Π½ΠΎΠ²… Π§ΠΈΡΠ°ΡΡ Π΅ΡΡ >
- Π‘ΠΎΠ΄Π΅ΡΠΆΠ°Π½ΠΈΠ΅
- ΠΡΠ΄Π΅ΡΠΆΠΊΠ°
- ΠΠΈΡΠ΅ΡΠ°ΡΡΡΠ°
- ΠΡΡΠ³ΠΈΠ΅ ΡΠ°Π±ΠΎΡΡ
- ΠΠΎΠΌΠΎΡΡ Π² Π½Π°ΠΏΠΈΡΠ°Π½ΠΈΠΈ
Π‘ΠΎΠ΄Π΅ΡΠΆΠ°Π½ΠΈΠ΅
- Π‘ΠΠΠ‘ΠΠ Π‘ΠΠΠ ΠΠ©ΠΠΠΠ
- 1. Π’ΠΎΠΊΡΠΈΠ½Ρ Bacillus cereus ΠΈΡ
ΡΠ΅Π³ΡΠ»ΡΡΠΎΡΡ
- 1. 1. ΠΠΈΠΊΡΠΎΠΎΡΠ³Π°Π½ΠΈΠ·ΠΌΡ Π³ΡΡΠΏΠΏΡ Π. cereus
- 1. 2. Π’ΠΎΠΊΡΠΈΠ½Ρ Π±Π°ΠΊΡΠ΅ΡΠΈΠΉ Π³ΡΡΠΏΠΏΡ Π. cereus
- 1. 2. 1. Π€ΠΎΡΡΠΎΠ»ΠΈΠΏΠ°Π·Ρ
- 1. 2. 2. ΠΠ½ΡΠ΅ΡΠΎΡΠΎΠΊΡΠΈΠ½Ρ: Π³Π΅ΠΌΠΎΠ»ΠΈΠ·ΠΈΠ½ BL. Π½Π΅Π³Π΅ΠΌΠΎΠ»ΠΈΡΠΈΡΠ΅ΡΠΊΠΈΠΉ ΡΠ½ΡΠ΅ΡΠΎΡΠΎΠΊΡΠΈΠ½, ΡΠΈΡΠΎΡΠΎΠΊΡΠΈΠ½ Π ΠΈ Π³Π΅ΠΌΠΎΠ»ΠΈΠ·ΠΈΠ½ II
- 1. 2. 3. ΠΡΡΠ³ΠΈΠ΅ Π³Π΅ΠΌΠΎΠ»ΠΈΠ·ΠΈΠ½Ρ Π. cereus: Π³Π΅ΠΌΠΎΠ»ΠΈΠ·ΠΈΠ½ III, ΡΠ΅ΡΠ΅ΠΎΠ»ΠΈΠ·ΠΈΠ½ Π
- 1. 2. 4. ΠΠ°Π»ΠΎ ΠΎΡ Π°ΡΠ°ΠΊΡΠ΅ΡΠΈΠ·ΠΎΠ²Π°Π½Π½ΡΠ΅ ΡΠΎΠΊΡΠΈΠ½Ρ: ΡΠ½ΡΠ΅ΡΠΎΡΠΎΠΊΡΠΈΠ½ FM ΠΈ ΡΠ½ΡΠ΅ΡΠΎΡΠΎΠΊΡΠΈΠ½ ΠΡΠ΅Π’
- 1. 3. Π Π΅Π³ΡΠ»ΡΡΠΎΡΡ Ρ
ΡΠΎΠΌΠΎΡΠΎΠΌΠ½ΡΡ
Π³Π΅ΠΌΠΎΠ»ΠΈΡΠΈΡΠ΅ΡΠΊΠΈΡ
ΡΠ°ΠΊΡΠΎΡΠΎΠ² ΠΏΠ°ΡΠΎΠ³Π΅Π½Π½ΠΎΡΡΠΈ
- 1. 3. 1. PlcR, ΡΠ΅Π³ΡΠ»ΡΡΠΎΡ ΡΠΎΡΡΠΎΠ»ΠΈΠΏΠ°Π·Ρ Π‘
- 1. 3. 2. HlyllR, ΡΠ΅Π³ΡΠ»ΡΡΠΎΡ Π³Π΅ΠΌΠΎΠ»ΠΈΠ·ΠΈΠ½Π° II
- 1. 3. 3. Fur, ΡΠ΅Π³ΡΠ»ΡΡΠΎΡ Π³ΠΎΠΌΠ΅ΠΎΡΡΠ°Π·Π° ΠΆΠ΅Π»Π΅Π·Π°
- 1. 3. 4. ΠΠ²ΡΡ ΠΊΠΎΠΌΠΏΠΎΠ½Π΅Π½ΡΠ½Π°Ρ ΡΠ΅Π΄ΠΎΠΊΡ ΡΡΠ²ΡΡΠ²ΠΈΡΠ΅Π»ΡΠ½Π°Ρ ΡΠΈΡΡΠ΅ΠΌΠ° ResD-ResE
- 1. 3. 5. Fnr, ΡΠ΅Π³ΡΠ»ΡΡΠΎΡ Π²ΠΎΡΡΡΠ°Π½ΠΎΠ²Π»Π΅Π½ΠΈΡ ΡΡΠΌΠ°ΡΠ°ΡΠ° ΠΈ Π½ΠΈΡΡΠ°ΡΠ°
- 1. 3. 6. FlhA ΡΠ΅Π³ΡΠ»ΠΈΡΡΠ΅Ρ ΡΠ΅ΠΊΡΠ΅ΡΠΈΡ ΠΠ« ΠΈ PC-PLC
- 2. 1. Π‘ΡΡΡΠΊΡΡΡΠ° ΠΊΠΎΡ-ΡΠ΅ΡΠΌΠ΅Π½ΡΠ° Π ΠΠΠ
- 2. 2. Π‘ΡΡΡΠΊΡΡΡΠ° Ρ ΠΎΠ»ΠΎΡΠ΅ΡΠΌΠ΅Π½ΡΠ°
- 2. 3. ΠΠ½ΠΈΡΠΈΠ°ΡΠΈΡ ΡΡΠ°Π½ΡΠΊΡΠΈΠΏΡΠΈΠΈ. ΠΡΠΎΠ±Π΅Π½Π½ΠΎΡΡΠΈ Π·Π°ΠΊΡΡΡΠΎΠ³ΠΎ ΠΊΠΎΠΌΠΏΠ»Π΅ΠΊΡΠ°
- 2. 4. Π‘ΡΡΡΠΊΡΡΡΠ° ΠΎΡΠΊΡΡΡΠΎΠ³ΠΎ ΠΊΠΎΠΌΠΏΠ»Π΅ΠΊΡΠ° [67]
- 2. 5. ΠΡΠΎΠ±Π΅Π½Π½ΠΎΡΡΠΈ ΡΡΡΡΠΊΡΡΡΡ ΠΈΠ½ΠΈΡΠΈΠΈΡΡΡΡΠ΅Π³ΠΎ ΡΡΠ°Π½ΡΠΊΡΠΈΠΏΡΠΈΡ ΠΊΠΎΠΌΠΏΠ»Π΅ΠΊΡΠ°. ΠΠ±ΠΎΡΡΠΈΠ²Π½Π°Ρ ΠΈΠ½ΠΈΡΠΈΠ°ΡΠΈΡ
- 2. 6. ΠΠ»ΠΎΠ½Π³Π°ΡΠΈΠΎΠ½Π½ΡΠΉ ΠΊΠΎΠΌΠΏΠ»Π΅ΠΊΡ [109]
- 2. 7. Π‘ΡΡΡΠΊΡΡΡΠ° Π°ΠΊΡΠΈΠ²Π½ΠΎΠ³ΠΎ ΡΠ΅Π½ΡΡΠ° ΡΠ΅ΡΠΌΠ΅Π½ΡΠ°
- 3. 1. Π‘ΡΡΡΠΊΡΡΡΠ½ΡΠ΅ ΡΠ»Π΅ΠΌΠ΅Π½ΡΡ ΠΏΡΠΎΠΌΠΎΡΠΎΡΠΎΠ²
- 3. 1. 1. ΠΠ°Π·Π°Π»ΡΠ½ΡΠ΅ «-10» ΠΈ «-35» ΡΠ»Π΅ΠΌΠ΅Π½ΡΡ
- 3. 1. 2. «-10 ΡΠ΄Π»ΠΈΠ½Π΅Π½Π½ΡΠΉ» ΡΠ»Π΅ΠΌΠ΅Π½Ρ
- 3. 1. 3. UP-ΡΠ»Π΅ΠΌΠ΅Π½Ρ
- 3. 1. 4. ΠΠΈΡΠΊΡΠΈΠΌΠΈΠ½Π°ΡΠΎΡ
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- Π― ΠΈΡΠΊΡΠ΅Π½Π½Π΅ Π±Π»Π°Π³ΠΎΠ΄Π°ΡΠ΅Π½ ΡΠ²ΠΎΠΈΠΌ Π½Π°ΡΡΠ½ΡΠΌ ΡΡΠΊΠΎΠ²ΠΎΠ΄ΠΈΡΠ΅Π»ΡΠΌ ΠΠΎΠ½ΡΡΠ°Π½ΡΠΈΠ½Ρ ΠΠΈΠΊΡΠΎΡΠΎΠ²ΠΈΡΡ Π‘Π΅Π²Π΅ΡΠΈΠ½ΠΎΠ²Ρ ΠΈ ΠΠ»Π΅ΠΊΡΠ°Π½Π΄ΡΡ Π‘Π΅ΡΠ³Π΅Π΅Π²ΠΈΡΡ Π‘ΠΎΠ»ΠΎΠ½ΠΈΠ½Ρ Π·Π° ΠΌΡΠ΄ΡΠΎΠ΅ ΡΡΠΊΠΎΠ²ΠΎΠ΄ΡΡΠ²ΠΎ ΠΈ ΠΏΠΎΠΌΠΎΡΡ ΠΏΡΠΈ Π²ΡΠΏΠΎΠ»Π½Π΅Π½ΠΈΠΈ Π΄Π°Π½Π½ΠΎΠΉ ΡΠ°Π±ΠΎΡΡ.
- Π― ΠΏΡΠΈΠ·Π½Π°ΡΠ΅Π»Π΅Π½ ΠΎΠΏΠΏΠΎΠ½Π΅Π½ΡΠ°ΠΌ ΠΈ ΡΠ΅ΡΠ΅Π½Π·Π΅Π½ΡΠ°ΠΌ Π·Π° ΠΊΡΠΈΡΠΈΡΠ΅ΡΠΊΠΈΠ΅ Π·Π°ΠΌΠ΅ΡΠ°Π½ΠΈΡ ΠΈ ΠΎΠ±ΡΡΠΆΠ΄Π΅Π½ΠΈΠ΅ ΡΠ°Π±ΠΎΡΡ.
- Π’Π°ΠΊΠΆΠ΅ Ρ Ρ ΠΎΡΡ Π²ΡΡΠ°Π·ΠΈΡΡ ΠΎΡΠΎΠ±ΡΡ ΠΏΡΠΈΠ·Π½Π°ΡΠ΅Π»ΡΠ½ΠΎΡΡΡ JI.C. ΠΡΠ°Π±ΠΎΠ²ΡΠΊΠΎΠΉ Π·Π° ΠΏΠΎΠΌΠΎΡΡ ΠΈ ΠΏΠΎΠ΄Π΄Π΅ΡΠΆΠΊΡ Π² ΠΎΡΠΎΡΠΌΠ»Π΅Π½ΠΈΠΈ ΠΎΠ³ΡΠΎΠΌΠ½ΠΎΠ³ΠΎ ΠΊΠΎΠ»ΠΈΡΠ΅ΡΡΠ²Π° Π΄ΠΎΠΊΡΠΌΠ΅Π½ΡΠΎΠ² ΡΠΎΠΏΡΡΡΡΠ²ΡΡΡΠΈΡ Π·Π°ΡΠΈΡΠ΅ ΠΊΠ°Π½Π΄ΠΈΠ΄Π°ΡΡΠΊΠΎΠΉ Π΄ΠΈΡΡΠ΅ΡΡΠ°ΡΠΈΠΈ.
- ΠΡΠΎΠ±ΡΡ Π±Π»Π°Π³ΠΎΠ΄Π°ΡΠ½ΠΎΡΡΡ Π²ΡΡΠ°ΠΆΠ°Ρ ΡΠ²ΠΎΠ΅ΠΉ ΠΌΠ°ΠΌΠ΅ ΠΠΈΠ½Π΅ ΠΠ°Π²Π»ΠΎΠ²Π½Π΅ Π¨Π°Π΄ΡΠΈΠ½ΠΎΠΉ Π·Π° ΠΌΠ½ΠΎΠ³ΠΎΠ»Π΅ΡΠ½ΡΡ ΠΏΠΎΠ΄Π΄Π΅ΡΠΆΠΊΡ, ΠΏΠΎΠΌΠΎΡΡ ΠΈ ΡΠΎΠΏΠ΅ΡΠ΅ΠΆΠΈΠ²Π°Π½ΠΈΠ΅.