Особенности генетической изменчивости вируса Эбола в процессе адаптации к морским свинкам
Диссертация
В результате первых работ, не включающих генетический анализ ВЭ, пониженную вирулентность для человека ВЭ-Судан по сравнению с ВЭ-Заир связывали с обнаружением большого количества дефектных вирусных частиц при его размножении в культуре клеток и в организме хозяина (Ellis D.S. et al., 1978; Ellis D.S. et al., 1979; Bowen E.T. et al., 1980; McCormick J.B. et al., 1983). Позже были определены… Читать ещё >
Содержание
- СПИСОК ИСПОЛЬЗОВАННЫХ СОКРАЩЕНИЙ
- 1. ОБЗОР ЛИТЕРАТУРЫ
- 1. 1. Семейство Filoviridae: общие сведения и классификация
- 1. 2. Клиническая и патогенетическая характеристика геморрагической лихорадки
- Эбола
- 1. 3. Строение генома вируса Эбола
- 1. 4. Генетическое разнообразие, происхождение и эволюция вируса Эбола
- 1. 5. Структура вириона и свойства белков вируса Эбола
- 1. 6. Эпидемиологическая характеристика геморрагической лихорадки Эбола. Природные резервуары и переносчики
- 1. 7. Инфекция Эбола у лабораторных животных и получение адаптированных штаммов
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